Endocrine effects of sublethal exposure to persistent organic pollutants (POPS) on silver carp (Hypophthalmichthys molitrix)
文献类型：期刊论文
| 作者 | Xu, Y; Zhang, J; Li, W; Schramm, KW; Kettrup, A |
| 刊名 | ENVIRONMENTAL POLLUTION
 |
| 出版日期 | 2002 |
| 卷号 | 120期号:3页码:683-690 |
| ISSN号 | 0269-7491 |
| 关键词 | POPs EROD UDPGT retinoids thyroid hormone silver carp |
| 通讯作者 | Xu, Y, Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol, Wuhan 430072, Peoples R China |
| 中文摘要 | Silver carp (Hypophthalmichthys molitrix) samples were collected from five selected sites that represent diverse levels of downgraded persistent organic pollutants (POPs) contamination in Ya-Er Lake in October 1999. Hepatic ethoxyresorufin-O-deethylase (EROD) and UDP glucuronosyltransferase (UDPGT) activities, hepatosomatic index (HSI), hepatic retinoids, serum thyroid hormones were measured. It was found that hepatic retinol and serum free 3,5,3'- tetraiodothyronine (FT3) significantly increased (P < 0.01) when both hepatic EROD and UDPGT activities significantly declined (P < 0.01) from pond 1 to 5 with decrease in the degree of pollution. This significant negative correlation (P < 0.01) suggests that the persistent organochlorinated contaminants could induce hepatic EROD and UDPGT activities, alter retinoid and thyroid hormone homeostasis, and finally lead to the reduction of retinol and FT3, the two biologically active forms of retinoids and thyroid hormone in silver carp of Ya-Er Lake. (C) 2002 Elsevier Science Ltd. All rights reserved. |
| 英文摘要 | Silver carp (Hypophthalmichthys molitrix) samples were collected from five selected sites that represent diverse levels of downgraded persistent organic pollutants (POPs) contamination in Ya-Er Lake in October 1999. Hepatic ethoxyresorufin-O-deethylase (EROD) and UDP glucuronosyltransferase (UDPGT) activities, hepatosomatic index (HSI), hepatic retinoids, serum thyroid hormones were measured. It was found that hepatic retinol and serum free 3,5,3'- tetraiodothyronine (FT3) significantly increased (P < 0.01) when both hepatic EROD and UDPGT activities significantly declined (P < 0.01) from pond 1 to 5 with decrease in the degree of pollution. This significant negative correlation (P < 0.01) suggests that the persistent organochlorinated contaminants could induce hepatic EROD and UDPGT activities, alter retinoid and thyroid hormone homeostasis, and finally lead to the reduction of retinol and FT3, the two biologically active forms of retinoids and thyroid hormone in silver carp of Ya-Er Lake. (C) 2002 Elsevier Science Ltd. All rights reserved. |
| 学科主题 | Environmental Sciences |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
| 类目[WOS] | Environmental Sciences |
| 研究领域[WOS] | Environmental Sciences & Ecology |
| 关键词[WOS] | TROUT ONCORHYNCHUS-MYKISS ; THYROID-HORMONE ; PHASE-I ; PATTERNS ; DIOXIN ; CHINA |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000179013200020 |
| 公开日期 | 2010-10-13 |
| 源URL | [http://ir.ihb.ac.cn/handle/152342/9780]  |
| 专题 | 水生生物研究所_中科院水生所知识产出（2009年前）_期刊论文 |
| 作者单位 | 1.Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol, Wuhan 430072, Peoples R China 2.GSF, Natl Res Ctr Environmm & Hlth, Inst Ecol Chem, D-85764 Neuherberg, Germany |
| 推荐引用方式 GB/T 7714 | Xu, Y,Zhang, J,Li, W,et al. Endocrine effects of sublethal exposure to persistent organic pollutants (POPS) on silver carp (Hypophthalmichthys molitrix)[J]. ENVIRONMENTAL POLLUTION,2002,120(3):683-690. |
| APA | Xu, Y,Zhang, J,Li, W,Schramm, KW,&Kettrup, A.(2002).Endocrine effects of sublethal exposure to persistent organic pollutants (POPS) on silver carp (Hypophthalmichthys molitrix).ENVIRONMENTAL POLLUTION,120(3),683-690. |
| MLA | Xu, Y,et al."Endocrine effects of sublethal exposure to persistent organic pollutants (POPS) on silver carp (Hypophthalmichthys molitrix)".ENVIRONMENTAL POLLUTION 120.3(2002):683-690. |
入库方式： OAI收割
来源：水生生物研究所
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