Hydroxyethylation of Achryranthes bidentata Polysaccharide and Investigation of Their Antitumor Activity
文献类型：期刊论文
| 作者 | Zhang J(张健) ; Tian GY(田庚元) |
| 刊名 | J. Carbohydr. Chem.
 |
| 出版日期 | 2005 |
| 卷号 | 24期号:7页码:685-696 |
| ISSN号 | 0732-8303 |
| 其他题名 | 牛膝多糖的羟乙基化及其衍生物的抗肿瘤活性 |
| 英文摘要 | The hydroxyethylated Achyranthes bidentata polysaccharides (Abps) were synthesized. The distribution of substituents in these derivatives was studied using HPLC and NMR analysis. The results show that the substituents are not homogeneously distributed along the Abps chain and the reactivity of the hydroxyl groups in the sugar units is OH‐4 ≫ OH‐3>OH‐6≈OH‐1. Bioassay showed that the derivative with a low degree of substitution (DS) was the best choice to inhibit the growth of Lewis pulmonary carcinoma. |
| 学科主题 | 生命有机化学 |
| 收录类别 | SCI |
| 原文出处 | http://dx.doi.org/10.1081/CAR-200064662 |
| 语种 | 英语 |
| WOS记录号 | WOS:000233088300002 |
| 公开日期 | 2013-03-04 |
| 源URL | [http://202.127.28.38/handle/331003/22766]  |
| 专题 | 上海有机化学研究所_生命有机化学国家重点实验室 |
| 推荐引用方式 GB/T 7714 | Zhang J,Tian GY. Hydroxyethylation of Achryranthes bidentata Polysaccharide and Investigation of Their Antitumor Activity[J]. J. Carbohydr. Chem.,2005,24(7):685-696. |
| APA | 张健,&田庚元.(2005).Hydroxyethylation of Achryranthes bidentata Polysaccharide and Investigation of Their Antitumor Activity.J. Carbohydr. Chem.,24(7),685-696. |
| MLA | 张健,et al."Hydroxyethylation of Achryranthes bidentata Polysaccharide and Investigation of Their Antitumor Activity".J. Carbohydr. Chem. 24.7(2005):685-696. |
入库方式： OAI收割
来源：上海有机化学研究所
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