Bitriazolyl acyclonucleosides synthesized via Huisgen reaction using internal alkynes show antiviral activity against tobacco mosaic virus
文献类型：期刊论文
| 作者 | Wang MH(王孟华) ; Zhu RZ(朱瑞志) ; Fan ZJ(范志金) ; Fu YF(付一峰) ; Feng L(冯樑) ; Yao JH(姚建华) ; Alain Maggiani ; Xia Y(夏熠) ; Qu FQ(曲凡琪) ; Peng L(彭玲) |
| 刊名 | Bioorg. Med. Chem. Lett.
 |
| 出版日期 | 2011 |
| 卷号 | 21期号:1页码:354-357 |
| ISSN号 | 0960-894X |
| 其他题名 | 用双取代炔烃通过HUISGEN反应合成具有抗烟草花叶病毒的Bitriazolyl acyclonucleosides |
| 通讯作者 | 彭玲 |
| 英文摘要 | A family of novel bitriazolyl acyclonucleosides were synthesized using a simple and convenient one-step synthetic procedure via the Huisgen reaction by addition of NaN3 onto triazole nucleosides bearing internal alkynyl groups introduced at the 5-position of the triazole ring. Some of the compounds exhibited interesting antiviral activity against tobacco mosaic virus, demonstrating the importance of the bitriazolyl motif for the observed antiviral activity. (C) 2010 Elsevier Ltd. All rights reserved. |
| 学科主题 | 有机化学 |
| 收录类别 | SCI |
| 原文出处 | http://dx.doi.org/10.1016/j.bmcl.2010.10.141 |
| 语种 | 英语 |
| WOS记录号 | WOS:000285544400072 |
| 公开日期 | 2013-03-11 |
| 源URL | [http://202.127.28.38/handle/331003/23744]  |
| 专题 | 上海有机化学研究所_计算机化学与化学信息学研究室 |
| 推荐引用方式 GB/T 7714 | Wang MH,Zhu RZ,Fan ZJ,et al. Bitriazolyl acyclonucleosides synthesized via Huisgen reaction using internal alkynes show antiviral activity against tobacco mosaic virus[J]. Bioorg. Med. Chem. Lett.,2011,21(1):354-357. |
| APA | 王孟华.,朱瑞志.,范志金.,付一峰.,冯樑.,...&彭玲.(2011).Bitriazolyl acyclonucleosides synthesized via Huisgen reaction using internal alkynes show antiviral activity against tobacco mosaic virus.Bioorg. Med. Chem. Lett.,21(1),354-357. |
| MLA | 王孟华,et al."Bitriazolyl acyclonucleosides synthesized via Huisgen reaction using internal alkynes show antiviral activity against tobacco mosaic virus".Bioorg. Med. Chem. Lett. 21.1(2011):354-357. |
入库方式： OAI收割
来源：上海有机化学研究所
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