Stereoselective Synthesis of beta-Hydroxyallenes with Multiple Contiguous Stereogenic Centers via Aldehyde Addition to alpha-Alkenyl-Substituted Zirconacyclopentenes
文献类型：期刊论文
| 作者 | Zhou YB(周叶兵) ; Chen JJ(陈敬金) ; Zhao CB(赵春波) ; Wang EJ(王二娟) ; Liu YH(刘元红) ; Li YX(李玉学) |
| 刊名 | J. Org. Chem.
 |
| 出版日期 | 2009 |
| 卷号 | 74期号:15页码:5326-5330 |
| ISSN号 | 0022-3263 |
| 其他题名 | 通过醛对alpha-烯基取代的锆杂环戊烯的加成反应立体选择性地合成多手性的β-联烯醇类化合物 |
| 通讯作者 | 刘元红 ; 李玉学 |
| 英文摘要 | A highly stereoselective methodology for the synthesis of beta-hydroxyallenes with multiple stereogenic centers including allenic axial chirality, as well as center chirality, via addition of alpha-alkenylzirconacyclopentenes to aldehyde is described, Remarkably, the reaction occurs with completely different chemoselectivity in comparison with the usual alkyl- or aryl-substituted zirconacyclopentenes; that means, the C-C bond formation occurred selectively at the alkenylic carbon substituted with phenyl or alkyl group, while in the latter cases, insertion of aldehydes into the alkyl-zirconium bond to afford seven-membered oxazirconacycles has usually been observed. |
| 学科主题 | 金属有机化学 |
| 收录类别 | SCI |
| 原文出处 | http://dx.doi.org/10.1021/jo900808k |
| 语种 | 英语 |
| WOS记录号 | WOS:000268480300025 |
| 公开日期 | 2013-03-11 |
| 源URL | [http://202.127.28.38/handle/331003/24269]  |
| 专题 | 上海有机化学研究所_金属有机化学国家重点实验室 |
| 推荐引用方式 GB/T 7714 | Zhou YB,Chen JJ,Zhao CB,et al. Stereoselective Synthesis of beta-Hydroxyallenes with Multiple Contiguous Stereogenic Centers via Aldehyde Addition to alpha-Alkenyl-Substituted Zirconacyclopentenes[J]. J. Org. Chem.,2009,74(15):5326-5330. |
| APA | 周叶兵,陈敬金,赵春波,王二娟,刘元红,&李玉学.(2009).Stereoselective Synthesis of beta-Hydroxyallenes with Multiple Contiguous Stereogenic Centers via Aldehyde Addition to alpha-Alkenyl-Substituted Zirconacyclopentenes.J. Org. Chem.,74(15),5326-5330. |
| MLA | 周叶兵,et al."Stereoselective Synthesis of beta-Hydroxyallenes with Multiple Contiguous Stereogenic Centers via Aldehyde Addition to alpha-Alkenyl-Substituted Zirconacyclopentenes".J. Org. Chem. 74.15(2009):5326-5330. |
入库方式： OAI收割
来源：上海有机化学研究所
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