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  4. 海岸带生物学与生物资源利用重点实验室
  5. 海岸带生物学与生物资源利用所重点实验室
Toxicological effects of environmentally relevant lead and zinc in halophyte Suaeda salsa by NMR-based metabolomics

文献类型：期刊论文

作者Wu, Huifeng1,2; Liu, Xiaoli1,2,3; Zhao, Jianmin1,2; Yu, Junbao1,2; Pang, Qiuying4,5; Feng, Jianghua
刊名ECOTOXICOLOGY
出版日期2012-11-01
卷号21期号:8页码:2363-2371
关键词Metal Toxicology Halophyte NMR Metabolite
ISSN号0963-9292
产权排序[Wu, Huifeng; Liu, Xiaoli; Zhao, Jianmin; Yu, Junbao] Chinese Acad Sci, Key Lab Coastal Zone Environm Proc, Yantai Inst Coastal Zone Res YIC, Yantai 264003, Shandong, Peoples R China; [Wu, Huifeng; Liu, Xiaoli; Zhao, Jianmin; Yu, Junbao] YICCAS, Shandong Prov Key Lab Coastal Zone Environm Proc, Yantai 264003, Shandong, Peoples R China; [Liu, Xiaoli] Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China; [Pang, Qiuying] NE Forestry Univ, Alkali Soil Nat Environm Sci Ctr, Harbin 150040, Heilongjiang, Peoples R China; [Pang, Qiuying] Minist Educ, Key Lab Saline Alkali Vegetat Ecol Restorat Oil F, Harbin 150040, Heilongjiang, Peoples R China
通讯作者Wu, HF (reprint author), Chinese Acad Sci, Key Lab Coastal Zone Environm Proc, Yantai Inst Coastal Zone Res YIC, Yantai 264003, Shandong, Peoples R China.,hfwu@yic.ac.cn
中文摘要Lead (Pb) and zinc (Zn) are two typical metal contaminants with high levels in both seawater and sediment in the intertidal zones of the Bohai Sea. Suaeda salsa is the pioneer halophyte plant in the intertidal zones of the Bohai Sea. In the present work, the short (1 week) and long term (1 month) toxicological effects of environmentally relevant concentrations of Pb and Zn were characterized in S. salsa using NMR-based metabolomics combined with antioxidant enzyme activities. After metal exposure for 1 week, no significant metabolic responses were detected in root tissues of S. salsa. The significant metabolic responses included the increase of isocaproate, glucose and fructose, and decrease of malate, citrate and sucrose in root tissues of S. salsa exposed to Pb for 1 month. The increased phosphocholine and betaine, and decreased choline were uniquely found in Zn-exposed samples. The metabolic changes including decreased malate, citrate and sucrose were detected in both Pb and Zn-exposed groups. These metabolic biomarkers revealed that both Pb and Zn exposures could induce osmotic stress and disturbances in energy metabolism in S. salsa after exposures for 1 month. Overall, this work demonstrates that metabolomics can be used to elucidate toxicological effects of environmentally relevant metal contaminants using halophyte S. salsa as the bioindicator.
英文摘要Lead (Pb) and zinc (Zn) are two typical metal contaminants with high levels in both seawater and sediment in the intertidal zones of the Bohai Sea. Suaeda salsa is the pioneer halophyte plant in the intertidal zones of the Bohai Sea. In the present work, the short (1 week) and long term (1 month) toxicological effects of environmentally relevant concentrations of Pb and Zn were characterized in S. salsa using NMR-based metabolomics combined with antioxidant enzyme activities. After metal exposure for 1 week, no significant metabolic responses were detected in root tissues of S. salsa. The significant metabolic responses included the increase of isocaproate, glucose and fructose, and decrease of malate, citrate and sucrose in root tissues of S. salsa exposed to Pb for 1 month. The increased phosphocholine and betaine, and decreased choline were uniquely found in Zn-exposed samples. The metabolic changes including decreased malate, citrate and sucrose were detected in both Pb and Zn-exposed groups. These metabolic biomarkers revealed that both Pb and Zn exposures could induce osmotic stress and disturbances in energy metabolism in S. salsa after exposures for 1 month. Overall, this work demonstrates that metabolomics can be used to elucidate toxicological effects of environmentally relevant metal contaminants using halophyte S. salsa as the bioindicator.
学科主题Ecology; Environmental Sciences; Toxicology
研究领域[WOS]Environmental Sciences & Ecology ; Toxicology
关键词[WOS]V-H+-ATPASE ; CADMIUM EXPOSURE ; ACCUMULATION ; SPECTROSCOPY ; EXPRESSION ; RESPONSES ; TOXICITY ; STRESS ; LEAVES ; PLANTS
收录类别SCI
资助信息National Science & Technology Pillar Program [2011BAC02B01]; Chinese Academy of Sciences
原文出处http://dx.doi.org/10.1007/s10646-012-0992-2
语种英语
WOS记录号WOS:000312664900026
公开日期2013-03-08
源URL[http://ir.yic.ac.cn/handle/133337/6067]  
专题烟台海岸带研究所_海岸带生物学与生物资源利用所重点实验室
烟台海岸带研究所_滨海湿地实验室
烟台海岸带研究所_中科院海岸带环境过程与生态修复重点实验室
作者单位1.Chinese Acad Sci, Key Lab Coastal Zone Environm Proc, Yantai Inst Coastal Zone Res YIC, Yantai 264003, Shandong, Peoples R China
2.YICCAS, Shandong Prov Key Lab Coastal Zone Environm Proc, Yantai 264003, Shandong, Peoples R China
3.Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China
4.NE Forestry Univ, Alkali Soil Nat Environm Sci Ctr, Harbin 150040, Heilongjiang, Peoples R China
5.Minist Educ, Key Lab Saline Alkali Vegetat Ecol Restorat Oil F, Harbin 150040, Heilongjiang, Peoples R China
推荐引用方式
GB/T 7714		 Wu, Huifeng,Liu, Xiaoli,Zhao, Jianmin,et al. Toxicological effects of environmentally relevant lead and zinc in halophyte Suaeda salsa by NMR-based metabolomics[J]. ECOTOXICOLOGY,2012,21(8):2363-2371.
APA Wu, Huifeng,Liu, Xiaoli,Zhao, Jianmin,Yu, Junbao,Pang, Qiuying,&Feng, Jianghua.(2012).Toxicological effects of environmentally relevant lead and zinc in halophyte Suaeda salsa by NMR-based metabolomics.ECOTOXICOLOGY,21(8),2363-2371.
MLA Wu, Huifeng,et al."Toxicological effects of environmentally relevant lead and zinc in halophyte Suaeda salsa by NMR-based metabolomics".ECOTOXICOLOGY 21.8(2012):2363-2371.

入库方式： OAI收割

来源：烟台海岸带研究所

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