Chemical constituents of Euphorbia tangutica
文献类型：期刊论文
| 作者 | Zhang, Ben-Yin1,5; Wang, Huan1; Luo, Xiao-Dong2; Du, Zhi-Zhi2; Wu, Hai-Feng3,4; Shen, Jian-Wei1; Zhang, Xiao-feng1 |
| 刊名 | natural product research
 |
| 出版日期 | 2012 |
| 卷号 | 26期号:24页码:2309-2315 |
| 关键词 | Euphorbiaceae Euphorbia tangutica phorbol-13-actate ergosterol cytotoxic activity |
| ISSN号 | 1478-6419 |
| 中文摘要 | sixteen known compounds isolated from the whole plants of euphorbia tangutica, including phorbol-13-actate (1) previously synthesised and obtained from a natural source for the first time, were evaluated in vitro against a panel of human cancer cell lines using the mtt method. among them, ergosterol (6) exhibited significant cytotoxic activity against hl-60 cell line with an ic50 value of 3.3 mu m, and 3 beta,5 alpha-dihydroxy-15 beta-cinnamoyloxy-14-oxolathyra-6z,12 e-diene (7) also displayed moderate activity. |
| 英文摘要 | sixteen known compounds isolated from the whole plants of euphorbia tangutica, including phorbol-13-actate (1) previously synthesised and obtained from a natural source for the first time, were evaluated in vitro against a panel of human cancer cell lines using the mtt method. among them, ergosterol (6) exhibited significant cytotoxic activity against hl-60 cell line with an ic50 value of 3.3 mu m, and 3 beta,5 alpha-dihydroxy-15 beta-cinnamoyloxy-14-oxolathyra-6z,12 e-diene (7) also displayed moderate activity. |
| WOS标题词 | science & technology ; physical sciences ; life sciences & biomedicine |
| 类目[WOS] | chemistry, applied ; chemistry, medicinal |
| 研究领域[WOS] | chemistry ; pharmacology & pharmacy |
| 关键词[WOS] | macrocyclic diterpenes ; toxicity ; esters |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000310608200004 |
| 公开日期 | 2013-03-15 |
| 源URL | [http://ir.nwipb.ac.cn/handle/363003/3738]  |
| 专题 | 西北高原生物研究所_中国科学院西北高原生物研究所 |
| 作者单位 | 1.Chinese Acad Sci, NW Inst Plateau Biol, Xining 810008, Peoples R China 2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China 3.Chinese Acad Med Sci, Inst Med Plant Dev, Beijing 100193, Peoples R China 4.Peking Union Med Coll, Beijing 100193, Peoples R China 5.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Ben-Yin,Wang, Huan,Luo, Xiao-Dong,et al. Chemical constituents of Euphorbia tangutica[J]. natural product research,2012,26(24):2309-2315. |
| APA | Zhang, Ben-Yin.,Wang, Huan.,Luo, Xiao-Dong.,Du, Zhi-Zhi.,Wu, Hai-Feng.,...&Zhang, Xiao-feng.(2012).Chemical constituents of Euphorbia tangutica.natural product research,26(24),2309-2315. |
| MLA | Zhang, Ben-Yin,et al."Chemical constituents of Euphorbia tangutica".natural product research 26.24(2012):2309-2315. |
入库方式： OAI收割
来源：西北高原生物研究所
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