Influence of dioxin and metal-contaminated sediment on phase I and II biotransformation enzymes in silver crucian carp
文献类型：期刊论文
| 作者 | Chen, GS; Xu, Y; Xu, LH; Zhang, YY; Schramm, KW; Kettrup, A |
| 刊名 | ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
 |
| 出版日期 | 1998-07-01 |
| 卷号 | 40期号:3页码:234-238 |
| 关键词 | ATLANTIC CROAKER TISSUES RAINBOW-TROUT OXIDATIVE STRESS CHANNEL CATFISH MILL EFFLUENTS GLUTATHIONE FISH TRANSFERASE INDUCTION EXPOSURE |
| ISSN号 | 0147-6513 |
| 通讯作者 | Chen, GS, Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol, Wuhan 430072, Peoples R China |
| 中文摘要 | Several biochemical responses were measured in silver crucian carp (Carassius auratus gibelio) after exposure to sediments obtained from contaminated Ya-Er Lake, No, 1 pond, and an unpolluted reference site, Honglian Lake. After 1 week of exposure, a significant induction of the phase I biotransformation enzyme (ethoxylresorufin-o-deethylase, EROD) was found (83-fold of control), whereas the phase II biotransformation enzyme (glutathione S-transferase, GST) exhibited a slight, but significant induction (1,4-fold of control) after 4 weeks of exposure. The level of cellular glutathione in the liver was also slightly elevated after 4 weeks of exposure. The delayed response of GST to the contaminants indicates that the phase I and phase II biotransformation enzymes are regulated differently in fish. The results suggest that EROD is a sensitive bioindicator to assess the toxicity of dioxin-contamined sediment in the laboratory, (C) 1998 Academic Press. |
| 英文摘要 | Several biochemical responses were measured in silver crucian carp (Carassius auratus gibelio) after exposure to sediments obtained from contaminated Ya-Er Lake, No, 1 pond, and an unpolluted reference site, Honglian Lake. After 1 week of exposure, a significant induction of the phase I biotransformation enzyme (ethoxylresorufin-o-deethylase, EROD) was found (83-fold of control), whereas the phase II biotransformation enzyme (glutathione S-transferase, GST) exhibited a slight, but significant induction (1,4-fold of control) after 4 weeks of exposure. The level of cellular glutathione in the liver was also slightly elevated after 4 weeks of exposure. The delayed response of GST to the contaminants indicates that the phase I and phase II biotransformation enzymes are regulated differently in fish. The results suggest that EROD is a sensitive bioindicator to assess the toxicity of dioxin-contamined sediment in the laboratory, (C) 1998 Academic Press. |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
| 学科主题 | Environmental Sciences; Toxicology |
| 类目[WOS] | Environmental Sciences ; Toxicology |
| 研究领域[WOS] | Environmental Sciences & Ecology ; Toxicology |
| 关键词[WOS] | ATLANTIC CROAKER TISSUES ; RAINBOW-TROUT ; OXIDATIVE STRESS ; CHANNEL CATFISH ; MILL EFFLUENTS ; GLUTATHIONE ; FISH ; TRANSFERASE ; INDUCTION ; EXPOSURE |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000074901000008 |
| 公开日期 | 2010-10-13 |
| 源URL | [http://ir.ihb.ac.cn/handle/152342/10232]  |
| 专题 | 水生生物研究所_中科院水生所知识产出（2009年前）_期刊论文 |
| 作者单位 | 1.Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol, Wuhan 430072, Peoples R China 2.GSF Forschungszentrum Umwelt & Gesundheit, Inst Ecol Chem, D-85764 Neuherberg, Germany |
| 推荐引用方式 GB/T 7714 | Chen, GS,Xu, Y,Xu, LH,et al. Influence of dioxin and metal-contaminated sediment on phase I and II biotransformation enzymes in silver crucian carp[J]. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY,1998,40(3):234-238. |
| APA | Chen, GS,Xu, Y,Xu, LH,Zhang, YY,Schramm, KW,&Kettrup, A.(1998).Influence of dioxin and metal-contaminated sediment on phase I and II biotransformation enzymes in silver crucian carp.ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY,40(3),234-238. |
| MLA | Chen, GS,et al."Influence of dioxin and metal-contaminated sediment on phase I and II biotransformation enzymes in silver crucian carp".ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY 40.3(1998):234-238. |
入库方式： OAI收割
来源：水生生物研究所
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