Does the urokinase receptor exist in a latent form?
文献类型：期刊论文
| 作者 | C. Yuan ; M. Huang |
| 刊名 | Cellular and Molecular Life Sciences
 |
| 出版日期 | 2007-05 |
| 卷号 | 64期号:9页码:1033-1037 |
| 关键词 | urokinase receptor urokinase latent form plasminogen-activator receptor tumor-cell invasion vitronectin-binding membrane-proteins in-vivo migration adhesion upar surface cancer |
| ISSN号 | 1420-682X |
| 中文摘要 | Multiple cellular functions of urokinase and its receptor are associated with the receptor's capability to interact with a number of ligands at the molecular level. The presence of urokinase is generally needed for the urokinase receptor to acquire this capability. Recent X-ray studies of the structure of the urokinase receptor in complex with either its ligand or peptide inhibitors demonstrate the flexibility of the domain organization of the receptor, suggesting that unliganded urokinase receptor may exist in a latent form that has a conformation different from its ligand-binding form. |
| 语种 | 英语 |
| 公开日期 | 2013-04-01 |
| 源URL | [http://ir.fjirsm.ac.cn/handle/350002/6845]  |
| 专题 | 福建物质结构研究所_中科院福建物质结构研究所_期刊论文 |
| 推荐引用方式 GB/T 7714 | C. Yuan,M. Huang. Does the urokinase receptor exist in a latent form?[J]. Cellular and Molecular Life Sciences,2007,64(9):1033-1037. |
| APA | C. Yuan,&M. Huang.(2007).Does the urokinase receptor exist in a latent form?.Cellular and Molecular Life Sciences,64(9),1033-1037. |
| MLA | C. Yuan,et al."Does the urokinase receptor exist in a latent form?".Cellular and Molecular Life Sciences 64.9(2007):1033-1037. |
入库方式： OAI收割
来源：福建物质结构研究所
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