Silver (I)-assisted enantiomeric analysis of ginsenosides using electrospray ionization tandem mass spectrometry
文献类型：期刊论文
| 作者 | Yu Q ; Yu BB ; Yang HM ; Li X ; Liu SY |
| 刊名 | journal of mass spectrometry
 |
| 出版日期 | 2012 |
| 卷号 | 47期号:10页码:1313-1321 |
| 关键词 | PERFORMANCE LIQUID-CHROMATOGRAPHY COLLISION-INDUCED DISSOCIATION NONAQUEOUS REVERSED-PHASE MALDI-TOF-MS METAL COMPLEXATION SHOTGUN LIPIDOMICS PANAX-GINSENG TRITERPENOID SAPONINS STRUCTURAL-ANALYSIS CELLULAR LIPIDOMES |
| ISSN号 | 1076-5174 |
| 通讯作者 | liu sy |
| 中文摘要 | for identification of ginsenoside enantiomers, electrospray ionization mass spectrometry (esi-ms) was used to generate silver complexes of the type [ginsenoside?+?ag]+. collision induced dissociation of the silver-ginsenoside complexes produced fragment ions by dehydration, allowing differentiation of ginsenoside enantiomers by the intensity of [m?+?ag?-?h2o]+ ion. in the meanwhile, an approach based on the distinct profiles of enantiomer-selective fragment ion intensity varied with collision energy was introduced to refine the identification and quantitation of ginsenoside enantiomers. five pairs of enantiomeric ginsenosides were distinguished and quantified on the basis of the distribution of fragment ion [m?+?ag?-?h2o]+. this method was also extended to the identification of other type of ginsenoside isomers such as ginsenoside rb2 and rb3. for demonstrating the practicability of this novel approach, it was utilized to analyze the molar ratio of 20-(s) and 20-(r) type enantiomeric ginsenosides in enantiomer mixture in red ginseng extract. the generation of characteristic fragment ion [m?+?ag?-?h2o]+ likely results from the reduction of potential energy barrier of dehydration because of the catalysis of silver ion. the mechanism of enantiomer identification of ginsenosides was discussed from the aspects of computational modeling and internal energy. copyright (c) 2012 john wiley & sons, ltd. |
| 收录类别 | SCI收录期刊论文 |
| 语种 | 英语 |
| WOS记录号 | WOS:000309396300006 |
| 公开日期 | 2013-04-23 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/47930]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Yu Q,Yu BB,Yang HM,et al. Silver (I)-assisted enantiomeric analysis of ginsenosides using electrospray ionization tandem mass spectrometry[J]. journal of mass spectrometry,2012,47(10):1313-1321. |
| APA | Yu Q,Yu BB,Yang HM,Li X,&Liu SY.(2012).Silver (I)-assisted enantiomeric analysis of ginsenosides using electrospray ionization tandem mass spectrometry.journal of mass spectrometry,47(10),1313-1321. |
| MLA | Yu Q,et al."Silver (I)-assisted enantiomeric analysis of ginsenosides using electrospray ionization tandem mass spectrometry".journal of mass spectrometry 47.10(2012):1313-1321. |
入库方式： OAI收割
来源：长春应用化学研究所
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