A simple and efficient method for the allylation of heteroarenes catalyzed by PdCl2
文献类型：期刊论文
| 作者 | Yuan FQ ; Sun FY ; Han FS |
| 刊名 | tetrahedron
 |
| 出版日期 | 2012 |
| 卷号 | 68期号:34页码:6837-6842 |
| 关键词 | ALLYLIC ALKYLATION NUCLEOPHILIC-SUBSTITUTION HETEROAROMATIC-COMPOUNDS SYNTHETIC EFFICIENCY BENZYLIC ALCOHOLS C-C INDOLES FUNCTIONALIZATION ACETATES ACIDS |
| ISSN号 | 0040-4020 |
| 通讯作者 | han fs |
| 中文摘要 | the pdcl2-catalyzed allylation of heteroarenes is presented. various heteroarenes including o-, n-, and s-based ones were allylated efficiently with a rich range of allylic acetates in the presence of only 2 mol % of pdcl2, without the need of bases/acids, additives, and external supporting ligands. in addition, the reactions were carried out under mild and simple conditions just by stirring the two reactants and catalyst in ch2cl2 at 60 degrees c. moreover, the by-product produced was non-toxic acetic acid. thus, the method presented in this work provides a general, clean, and operationally simple approach for the functionalization of heteroarenes. finally, a preliminary mechanistic study suggested that the pd(ii) may be reduced in situ by the heteroarenes to pd(0), which serves as the active metal center to catalyze the following allylations of heteroarenes via a tsuji trost pathway. (c) 2012 elsevier ltd. all rights reserved. |
| 收录类别 | SCI收录期刊论文 |
| 语种 | 英语 |
| WOS记录号 | WOS:000306981800006 |
| 公开日期 | 2013-04-23 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/47989]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Yuan FQ,Sun FY,Han FS. A simple and efficient method for the allylation of heteroarenes catalyzed by PdCl2[J]. tetrahedron,2012,68(34):6837-6842. |
| APA | Yuan FQ,Sun FY,&Han FS.(2012).A simple and efficient method for the allylation of heteroarenes catalyzed by PdCl2.tetrahedron,68(34),6837-6842. |
| MLA | Yuan FQ,et al."A simple and efficient method for the allylation of heteroarenes catalyzed by PdCl2".tetrahedron 68.34(2012):6837-6842. |
入库方式： OAI收割
来源：长春应用化学研究所
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