Rheological Properties of Cysteine-Containing Elastin-Like Polypeptide Solutions and Hydrogels
文献类型：期刊论文
| 作者 | Xu DH ; Asai D ; Chilkoti A ; Craig SL |
| 刊名 | biomacromolecules
 |
| 出版日期 | 2012 |
| 卷号 | 13期号:8页码:2315-2321 |
| 关键词 | SUPRAMOLECULAR POLYMER NETWORKS DRUG-DELIVERY SYSTEMS POLYVINYL-ALCOHOL TISSUE-REPAIR BEHAVIOR DILUTE GELS |
| ISSN号 | 1525-7797 |
| 通讯作者 | chilkoti a |
| 中文摘要 | the theological properties of cysteine-containing elastin-like polypeptide (cys-elp) solutions and cys-elp hydrogels are reported. the cys-elp solutions exhibit a surprisingly high apparent viscosity at low shear rate. the high viscosity is attributed to the formation of an interfacial cross-linked "skin" at the sample surface, rather than the bulk of the cys-elp solution. at higher shear rate, the interfacial cross-linked film breaks, and its influence on the viscosity of the cys-elp solution can be ignored. cys-elp hydrogels are formed by mixing cys-elp and hydrogen peroxide (h2o2). at fixed concentration of cys-elp, the gelation time can be tuned by the concentration of h2o2. cys-elp hydrogels have the typical characteristics of covalent cross linked networks, as the storage moduli are larger than the loss moduli and are independent of frequency in dynamic oscillatory frequency sweep experiments. the plateau moduli obtained from linear frequency sweep experiments are much lower than those estimated from the limber of thiol groups along the cys-elp chain, indicating that only a small fraction of thiols form elastically active cross links from the small value of the fraction of elastically active cross links, the cys-elp hydrogel is concluded to be an inhomogenous network. under steady shear, a 2.5 wt % cys-elp hydrogel shear thickens at shear rates lower than that necessary for fracture. |
| 收录类别 | SCI收录期刊论文 |
| 语种 | 英语 |
| WOS记录号 | WOS:000307422300013 |
| 公开日期 | 2013-04-23 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/48022]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Xu DH,Asai D,Chilkoti A,et al. Rheological Properties of Cysteine-Containing Elastin-Like Polypeptide Solutions and Hydrogels[J]. biomacromolecules,2012,13(8):2315-2321. |
| APA | Xu DH,Asai D,Chilkoti A,&Craig SL.(2012).Rheological Properties of Cysteine-Containing Elastin-Like Polypeptide Solutions and Hydrogels.biomacromolecules,13(8),2315-2321. |
| MLA | Xu DH,et al."Rheological Properties of Cysteine-Containing Elastin-Like Polypeptide Solutions and Hydrogels".biomacromolecules 13.8(2012):2315-2321. |
入库方式： OAI收割
来源：长春应用化学研究所
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