Nanostructured glass-ceramic coatings for orthopaedic applictions
文献类型：期刊论文
| 作者 | Guocheng Wang ; Zufu Lu ; Liu XY(刘宣勇) ; Xiaming Zhou ; Ding CX(丁传贤) ; Hala Zreiqat |
| 刊名 | Journal of the Royal Society Interface
 |
| 出版日期 | 2011-02-03 |
| 卷号 | 8期号:61 |
| ISSN号 | 1742-5689 |
| 其他题名 | Nanostructured glass-ceramic coatings for orthopaedic applictions |
| 通讯作者 | Hala Zreiqat |
| 中文摘要 | Glass–ceramics have attracted much attention in the biomedical field, as they provide great possibilities to manipulate their properties by post-treatments, including strength, degradation rate and coefficient of thermal expansion. In this work, hardystonite (HT; Ca2ZnSi2O7) and sphene (SP; CaTiSiO5) glass–ceramic coatings with nanostructures were prepared by a plasma spray technique using conventional powders. The bonding strength and Vickers hardness for HT and SP coatings are higher than the reported values for plasma-sprayed hydroxyapatite coatings. Both types of coatings release bioactive calcium (Ca) and silicon (Si) ions into the surrounding environment. Mineralization test in cell-free culture medium showed that many mushroom-like Ca and phosphorus compounds formed on the HT coatings after 5 h, suggesting its high acellular mineralization ability. Primary human osteoblasts attach, spread and proliferate well on both types of coatings. Higher proliferation rate was observed on the HT coatings compared with the SP coatings and uncoated Ti-6Al-4V alloy, probably due to the zinc ions released from the HT coatings. Higher expression levels of Runx2, osteopontin and type I collagen were observed on both types of coatings compared with Ti-6Al-4V alloy, possibly due to the Ca and Si released from the coatings. Results of this study point to the potential use of HT and SP coatings for orthopaedic applications. Keywords: plasma spray; orthopaedic; titanium alloy; nanostructure; osteogenic genes; glass–ceramic |
| 学科主题 | 生物材料 |
| 收录类别 | SCI收录 |
| 原文出处 | http://rsif.royalsocietypublishing.org/content/8/61/1192.full?sid=92ef66fe-e6ac-47c4-bcb1-e494a1419c3d |
| 公开日期 | 2012-07-04 |
| 源URL | [http://ir.sic.ac.cn/handle/331005/957]  |
| 专题 | 上海硅酸盐研究所_生物材料与组织工程研究中心_期刊论文 |
| 推荐引用方式 GB/T 7714 | Guocheng Wang,Zufu Lu,Liu XY,et al. Nanostructured glass-ceramic coatings for orthopaedic applictions[J]. Journal of the Royal Society Interface,2011,8(61). |
| APA | Guocheng Wang,Zufu Lu,刘宣勇,Xiaming Zhou,丁传贤,&Hala Zreiqat.(2011).Nanostructured glass-ceramic coatings for orthopaedic applictions.Journal of the Royal Society Interface,8(61). |
| MLA | Guocheng Wang,et al."Nanostructured glass-ceramic coatings for orthopaedic applictions".Journal of the Royal Society Interface 8.61(2011). |
入库方式： OAI收割
来源：上海硅酸盐研究所
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