中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Structural characterization and immunological activities of the water-soluble oligosaccharides isolated from the Panax ginseng roots

文献类型:期刊论文

作者Wan DB ; Jiao LL ; Yang HM ; Liu SY
刊名planta
出版日期2012
卷号235期号:6页码:1289-1297
关键词ACTIVE ANTIRETROVIRAL THERAPY TANDEM MASS-SPECTROMETRY KOREAN RED GINSENG POLYSACCHARIDES SAPONIN ASSAY
ISSN号0032-0935
通讯作者liu sy
中文摘要water-soluble ginseng oligosaccharides (designated as wgos) with a degree of polymerization ranging from 2 to 10 were obtained from warm-water extract of panax ginseng roots, and fractionated into five purified fractions (i.e., wgos-0, wgos-1, wgos-2, wgos-3, and wgos-4) by gel-filtration chromatography. in order to ascertain the monosaccharide residues in the wgos, a technique that combines acid hydrolysis and high-performance liquid chromatography was employed. it was found that only glucose residues were present in the wgos. fourier transform infrared spectroscopy and electrospray ionization tandem mass spectrometry provided the sequence, linkage, and configuration information. it is noteworthy that alpha-glcp-(1 -> 6)-alpha-glcp, alpha-glcp-(1 -> 6)-alpha-glcp-(1 -> 4)-alpha-glcp, alpha-glcp-(1 -> 6)-alpha-glcp-(1 -> 6)-alpha-glcp-(1 -> 4)-alpha-glcp, and other six malto-oligosaccharides (i.e., maltopentaose, maltohexaose, maltoheptaose, maltooctaose, maltononaose, and maltodecaose) were detected in ginseng. preliminary immunological tests in vitro indicated that wgos were potent b and t-cell stimulators and wgos-1 has the highest immunostimulating effect on lymphocyte proliferation among those purified fractions. it is hoped that the wgos will be developed into functional food or medicine.
收录类别SCI收录期刊论文
语种英语
WOS记录号WOS:000304621200014
公开日期2013-05-20
源URL[http://ir.ciac.jl.cn/handle/322003/48122]  
专题长春应用化学研究所_长春应用化学研究所知识产出_期刊论文
推荐引用方式
GB/T 7714
Wan DB,Jiao LL,Yang HM,et al. Structural characterization and immunological activities of the water-soluble oligosaccharides isolated from the Panax ginseng roots[J]. planta,2012,235(6):1289-1297.
APA Wan DB,Jiao LL,Yang HM,&Liu SY.(2012).Structural characterization and immunological activities of the water-soluble oligosaccharides isolated from the Panax ginseng roots.planta,235(6),1289-1297.
MLA Wan DB,et al."Structural characterization and immunological activities of the water-soluble oligosaccharides isolated from the Panax ginseng roots".planta 235.6(2012):1289-1297.

入库方式: OAI收割

来源:长春应用化学研究所

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