DNA-Hosted Copper Nanoclusters for Fluorescent Identification of Single Nucleotide Polymorphisms
文献类型：期刊论文
| 作者 | Jia XF ; Li J ; Han L ; Ren JT ; Yang X ; Wang EK |
| 刊名 | acs nano
 |
| 出版日期 | 2012 |
| 卷号 | 6期号:4页码:3311-3317 |
| 关键词 | SILVER NANOCLUSTERS CIRCULAR-DICHROISM GOLD NANOCLUSTERS PROBE NANOPARTICLES CLUSTERS COMPLEX IONS |
| ISSN号 | 1936-0851 |
| 通讯作者 | wang ek |
| 中文摘要 | metal nanoclusters have received considerable interest due to their unique properties and potential applications in numerous fields. particularly, newly emerging cu nanoclusters offer excellent potential as functional biological probes. in this work, we for the first time report that the fluorescence of dna-hosted cu nanoclusters is very sensitive to base type located in the major groove. this intriguing finding provides a sensitive fluorimetric diagnostic of the mismatch type in a specific dna sequence, which is difficult to achieve by traditional methods. furthermore, the research results have shed some light on the luminescent mechanism of cu nanoclusters. owing to its high specificity and easy operation without rigorously controlled temperature and arduous probe dna design, it is expected that the proposed procedure can provide a tool for early diagnosis and risk assessment of malignancy. |
| 收录类别 | SCI收录期刊论文 |
| 语种 | 英语 |
| WOS记录号 | WOS:000303099300053 |
| 公开日期 | 2013-05-22 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/48243]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Jia XF,Li J,Han L,et al. DNA-Hosted Copper Nanoclusters for Fluorescent Identification of Single Nucleotide Polymorphisms[J]. acs nano,2012,6(4):3311-3317. |
| APA | Jia XF,Li J,Han L,Ren JT,Yang X,&Wang EK.(2012).DNA-Hosted Copper Nanoclusters for Fluorescent Identification of Single Nucleotide Polymorphisms.acs nano,6(4),3311-3317. |
| MLA | Jia XF,et al."DNA-Hosted Copper Nanoclusters for Fluorescent Identification of Single Nucleotide Polymorphisms".acs nano 6.4(2012):3311-3317. |
入库方式： OAI收割
来源：长春应用化学研究所
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