Decorated graphene sheets for label-free DNA impedance biosensing
文献类型：期刊论文
| 作者 | Hu YW ; Wang KK ; Zhang QX ; Li FH ; Wu TS ; Niu L |
| 刊名 | biomaterials
 |
| 出版日期 | 2012 |
| 卷号 | 33期号:4页码:1097-1106 |
| 关键词 | CARBON-PASTE ELECTRODES METHYLENE-BLUE ELECTROCHEMICAL DETECTION PERYLENE BISIMIDES GRAPHITE OXIDE HYBRIDIZATION NANOSHEETS NANOTUBES PLATFORM SENSITIVITY |
| ISSN号 | 0142-9612 |
| 通讯作者 | niu l |
| 中文摘要 | an efficient dna impedance biosensing platform is constructed, in which positively charged n,n-bis-(1-aminopropyl-3-propylimidazol salt)-3,4,9,10-perylene tetracarboxylic acid diimide (pdi) is anchored to graphene sheets. the pi-pi stacking and electronic interactions are elucidated by the distinct absorption features in uv-vis spectra and by quenching perylene fluorescence in contact with graphene. the rational design and tailoring of graphene surface invest it with desired properties (dispersive, structural, photoelectrical and conductive, etc.) and boost its application. electrostatic interaction between pdi's positively charged imidazole rings and negatively charged phosphate backbones of single-stranded dna (ssdna) facilitates ssdna immobilization. this manner is different from these mainly based on the attraction between the rings in dna bases and the hexagonal cells of graphene, which is disturbed after hybridization and causes the leaving of formed double-stranded dna from graphene surface. the electrostatic ssdna grafting occupies phosphate backbones and particularly leaves the bases available for efficient hybridization. dna immobilization and hybridization lead to pdi/graphene interfacial property changes, which are monitored by electrochemical impedance spectroscopy and adopted as the analytical signal. the conserved sequence of the pol gene of human immunodeficiency virus 1 is satisfactorily detected via this pdi/graphene platform and shows high reproducibility, selectivity. (c) 2011 elsevier ltd. all rights reserved. |
| 收录类别 | SCI收录期刊论文 |
| 语种 | 英语 |
| WOS记录号 | WOS:000298273400011 |
| 公开日期 | 2013-06-08 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/48363]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Hu YW,Wang KK,Zhang QX,et al. Decorated graphene sheets for label-free DNA impedance biosensing[J]. biomaterials,2012,33(4):1097-1106. |
| APA | Hu YW,Wang KK,Zhang QX,Li FH,Wu TS,&Niu L.(2012).Decorated graphene sheets for label-free DNA impedance biosensing.biomaterials,33(4),1097-1106. |
| MLA | Hu YW,et al."Decorated graphene sheets for label-free DNA impedance biosensing".biomaterials 33.4(2012):1097-1106. |
入库方式： OAI收割
来源：长春应用化学研究所
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