Controlled release of drug via tuning electrospun polymer carrier
文献类型：期刊论文
| 作者 | Song XF ; Gao ZT ; Ling FG ; Chen XS |
| 刊名 | journal of polymer science part b-polymer physics
 |
| 出版日期 | 2012 |
| 卷号 | 50期号:3页码:221-227 |
| 关键词 | POLY(LACTIC ACID) NANOFIBERS FIBERS MEMBRANES MATRIX SCAFFOLDS PEPTIDES SYSTEMS JETS |
| ISSN号 | 0887-6266 |
| 通讯作者 | chen xs |
| 中文摘要 | medicated-fibers have been obtained through electrospinning after rifampin was dissolved in poly (lactic acid)/chloroform solution. the relationship between polymer variables [such as concentration, molecular weight (mw), and introducing hydrophilic block] and drug release from the electrospun fibers is disclosed. the results show that polymeric concentration and mw are crucial for producing the medicated fibers, which influence not only the morphology of the medicated-fiber but also drug release rate from fiber. at the same mw, the drug release rate decreases with the increase of spinning concentration. at two different mw blends, drug release behaviors change. when the low mw content is in a dominant position, drug release rate depends largely on mixing ratio of two mw contents; on the other hand, drug release rate is also dependent on concentration of spinning fluid. in addition, the block copolymer [poly-l-lactic acid (plla)-polyethylene glycol-plla] shows faster release rate as compared to homopolymer (plla). (c) 2011 wiley periodicals, inc. j polym sci part b: polym phys, 50: 221-227, 2011 |
| 收录类别 | SCI收录期刊论文 |
| 语种 | 英语 |
| WOS记录号 | WOS:000298481400008 |
| 公开日期 | 2013-06-08 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/48366]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Song XF,Gao ZT,Ling FG,et al. Controlled release of drug via tuning electrospun polymer carrier[J]. journal of polymer science part b-polymer physics,2012,50(3):221-227. |
| APA | Song XF,Gao ZT,Ling FG,&Chen XS.(2012).Controlled release of drug via tuning electrospun polymer carrier.journal of polymer science part b-polymer physics,50(3),221-227. |
| MLA | Song XF,et al."Controlled release of drug via tuning electrospun polymer carrier".journal of polymer science part b-polymer physics 50.3(2012):221-227. |
入库方式： OAI收割
来源：长春应用化学研究所
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