Designing bifunctionalized gold nanoparticle for colorimetric detection of Pb2+ under physiological condition
文献类型：期刊论文
| 作者 | Zhu DR ; Li XK ; Liu X ; Wang JN ; Wang ZX |
| 刊名 | biosensors & bioelectronics
 |
| 出版日期 | 2012 |
| 卷号 | 31期号:1页码:505-509 |
| 关键词 | LEVEL LEAD-EXPOSURE SELECTIVE DETECTION QUANTUM DOTS LIVING CELLS MERCURY(II) TOXICITY IONS ACID DISCRIMINATION COPPER(II) |
| ISSN号 | 0956-5663 |
| 通讯作者 | wang zx |
| 中文摘要 | in the present work, a kind of peptide functionalized gold nanoparticle (aunp) has been synthesized and employed for colorimetric detection of pb2+ in both aqueous solution and living cell. the aunps are capped by two peptide ligands: glutathione (gsh) and pentapeptide (calnn). the gsh is used as a functional group for selectively sensing pb2+ by coordination reaction, and calnn is employed as a stabilize ligand for improving the stability of aunps under physiological condition, respectively. the aunp enables to strongly interact with pb2+ that leads to distinct color change of solution. under the optimized molar ratio of gsh to calnn on the aunp surface, the colorimetric assay for detecting pb2+ in living cell downs to 2.9 fmol pb(2+)per cell (3 times of standard deviation, 3 sigma) with linear relationship from 2.9 to 37.7 fmol pb2+ per cell. in addition, the method also shows highly selective detection toward pb2+ against other common metal ions in both aqueous solution and living cell. (c) 2011 elsevier b.v. all rights reserved. |
| 收录类别 | SCI收录期刊论文 |
| 语种 | 英语 |
| WOS记录号 | WOS:000300468400079 |
| 公开日期 | 2013-06-09 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/48388]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Zhu DR,Li XK,Liu X,et al. Designing bifunctionalized gold nanoparticle for colorimetric detection of Pb2+ under physiological condition[J]. biosensors & bioelectronics,2012,31(1):505-509. |
| APA | Zhu DR,Li XK,Liu X,Wang JN,&Wang ZX.(2012).Designing bifunctionalized gold nanoparticle for colorimetric detection of Pb2+ under physiological condition.biosensors & bioelectronics,31(1),505-509. |
| MLA | Zhu DR,et al."Designing bifunctionalized gold nanoparticle for colorimetric detection of Pb2+ under physiological condition".biosensors & bioelectronics 31.1(2012):505-509. |
入库方式： OAI收割
来源：长春应用化学研究所
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