Sesquineolignans and Terpene-Sesquineolignans: Anti-Acetylcholinesterase Constituents from Illicium simonsii
文献类型：期刊论文
| 作者 | Dong, Chuanfu1,2; Liu, Lei1,2; Li, Xiaonian1; Guan, Zhengye1,2; Luo, Huairong1 ; Wang, Yifen1
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| 刊名 | PLANTA MEDICA
 |
| 出版日期 | 2013-03-01 |
| 卷号 | 79期号:5页码:338-347 |
| 关键词 | Illiciaceae Illicium simonsii sesquineolignans terpene-sesquineolignans anti-AChE activity |
| ISSN号 | 0032-0943 |
| 通讯作者 | Wang, YF (reprint author), Chinese Acad Sci, Kunming Inst Bot, 132 Lanhei Rd, Kunming 650201, Yunnan, Peoples R China. ; wangyifen@mail.kib.ac.cn |
| 英文摘要 | Chemical investigation of the aerial parts of Illicium simonsii resulted in the isolation of nine new compounds, simonsols A-E (1-5), simonsins A-B (7-8), terpene-sesquineolignans, clovane-dunnianol (9), and p-menthadunnianol (10). Compound 5 was equilibrated with 7 as an inseparable mixture. The structures were elucidated by extensive NMR and MS analysis. Compounds 9, 10, and the mixture of 5 and 7 moderately inhibited acetylcholinesterase with IC50 values of 4.58 mu M, 6.55 mu M, and 10.34 mu M, respectively. |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
| 学科主题 | Plant Sciences; Pharmacology & Pharmacy |
| 类目[WOS] | Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy |
| 研究领域[WOS] | Plant Sciences ; Pharmacology & Pharmacy |
| 关键词[WOS] | PRENYLATED C-6-C-3 COMPOUNDS ; ACETYLCHOLINE ; DERIVATIVES ; DUNNIANUM ; BARK |
| 收录类别 | SCI |
| 资助信息 | National Natural Science Foundation [20872148]; Yunnan provincial government [20080A007]; 100 Talents Program of the Chinese Academy of Sciences [0931211022] |
| 语种 | 英语 |
| WOS记录号 | WOS:000316800900006 |
| 公开日期 | 2013-06-08 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/16467]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China 2.Grad Univ Chinese Acad Sci, Beijing, Peoples R China |
| 推荐引用方式 GB/T 7714 | Dong, Chuanfu,Liu, Lei,Li, Xiaonian,et al. Sesquineolignans and Terpene-Sesquineolignans: Anti-Acetylcholinesterase Constituents from Illicium simonsii[J]. PLANTA MEDICA,2013,79(5):338-347. |
| APA | Dong, Chuanfu,Liu, Lei,Li, Xiaonian,Guan, Zhengye,Luo, Huairong,&Wang, Yifen.(2013).Sesquineolignans and Terpene-Sesquineolignans: Anti-Acetylcholinesterase Constituents from Illicium simonsii.PLANTA MEDICA,79(5),338-347. |
| MLA | Dong, Chuanfu,et al."Sesquineolignans and Terpene-Sesquineolignans: Anti-Acetylcholinesterase Constituents from Illicium simonsii".PLANTA MEDICA 79.5(2013):338-347. |
入库方式： OAI收割
来源：昆明植物研究所
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