Synthesis of phospholipid monolayer membrane functionalized graphene for drug delivery
文献类型：期刊论文
| 作者 | Liu JY ; Guo SJ ; Han L ; Wang TS ; Hong W ; Liu YQ ; Wang EK |
| 刊名 | journal of materials chemistry
 |
| 出版日期 | 2012 |
| 卷号 | 22期号:38页码:20634-20640 |
| 关键词 | BILAYER-LIPID MEMBRANES CARBON NANOTUBES GOLD NANOPARTICLES LIPOSOMES DOXORUBICIN WATER OXIDE DNA ELECTRODE RELEASE |
| ISSN号 | 0959-9428 |
| 通讯作者 | liu yq |
| 中文摘要 | in this contribution, lipid monolayer membrane functionalized graphene sheets were prepared using a facile method. interactions between the graphene and different types of liposomes, including charged and neutral, were also investigated. we found that the anionic liposomes could spontaneously self-organize into lipid monolayer membranes, partially covering the surface of graphene sheets. the resultant lipid monolayer functionalized graphene nanomaterials exhibited high stability in aqueous solution and an excellent performance as carrier for loading the anticancer drug, doxorubicin (dox), with a high loading capacity of 70%. the loaded drug can be released under ph control. 10% and 14% of the bound dox was released after 54 h at ph 10.0 and 7.0, respectively. whereas, about 70% of dox was released after 54 h at ph 5.0. |
| 收录类别 | SCI收录期刊论文 |
| 语种 | 英语 |
| WOS记录号 | WOS:000308658600076 |
| 公开日期 | 2013-06-30 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/48464]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Liu JY,Guo SJ,Han L,et al. Synthesis of phospholipid monolayer membrane functionalized graphene for drug delivery[J]. journal of materials chemistry,2012,22(38):20634-20640. |
| APA | Liu JY.,Guo SJ.,Han L.,Wang TS.,Hong W.,...&Wang EK.(2012).Synthesis of phospholipid monolayer membrane functionalized graphene for drug delivery.journal of materials chemistry,22(38),20634-20640. |
| MLA | Liu JY,et al."Synthesis of phospholipid monolayer membrane functionalized graphene for drug delivery".journal of materials chemistry 22.38(2012):20634-20640. |
入库方式： OAI收割
来源：长春应用化学研究所
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