A label-free real time fluorometric assay for protease and inhibitor screening with a released heme
文献类型：期刊论文
| 作者 | Li WY ; Chen J ; Jiao HP ; Zhang QF ; Zhou HP ; Yu C |
| 刊名 | chemical communications
 |
| 出版日期 | 2012 |
| 卷号 | 48期号:81页码:10123-10125 |
| 关键词 | ACETYLCHOLINESTERASE ACTIVITY DRUG DISCOVERY PERYLENE PROBE TRYPSIN |
| ISSN号 | 1359-7345 |
| 通讯作者 | yu c |
| 中文摘要 | a label free continuous assay for protease activity and inhibitor screening has been developed. a protease (trypsin) could digest hemoglobin. free heme molecules were released. strong pi-pi stacking and hydrophobic interactions with the perylene probe resulted in efficient quenching of the probe's monomer fluorescence. |
| 收录类别 | SCI收录期刊论文 |
| 语种 | 英语 |
| WOS记录号 | WOS:000308827600014 |
| 公开日期 | 2013-06-30 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/48470]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Li WY,Chen J,Jiao HP,et al. A label-free real time fluorometric assay for protease and inhibitor screening with a released heme[J]. chemical communications,2012,48(81):10123-10125. |
| APA | Li WY,Chen J,Jiao HP,Zhang QF,Zhou HP,&Yu C.(2012).A label-free real time fluorometric assay for protease and inhibitor screening with a released heme.chemical communications,48(81),10123-10125. |
| MLA | Li WY,et al."A label-free real time fluorometric assay for protease and inhibitor screening with a released heme".chemical communications 48.81(2012):10123-10125. |
入库方式： OAI收割
来源：长春应用化学研究所
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