DNA-templated silver nanoclusters-graphene oxide nanohybrid materials: a platform for label-free and sensitive fluorescence turn-on detection of multiple nucleic acid targets
文献类型：期刊论文
| 作者 | Tao Y ; Lin YH ; Huang ZZ ; Ren JS ; Qu XG |
| 刊名 | analyst
 |
| 出版日期 | 2012 |
| 卷号 | 137期号:11页码:2588-2592 |
| 关键词 | MOLECULAR BEACONS GOLD NANOPARTICLES PROBES MICROARRAY SYSTEMS |
| ISSN号 | 0003-2654 |
| 通讯作者 | ren js |
| 中文摘要 | in this study, we develop an efficient method for multiple dna detection by exploring silver nanoclusters (agncs)-graphene oxide (go) nanohybrid materials. because of the extraordinarily high quenching efficiency of go, the ssdna-agncs probe exhibits minimal background fluorescence, while strong emission is observed when it forms a double helix with the specific target dna, leading to a high signal-to-background ratio. therefore the agncs-go nanohybrid materials can be successfully applied for dna detection. the system described here exhibits not only high sensitivity with a detection limit of 1 nm, but also an excellent differentiation ability for single-base mismatched sequences. in addition, by exploring agncs as signal reporters and go as the nanoquencher, this approach avoids labeling the probe dna or target dna, which offers the advantages of simplicity and cost efficiency. moreover, the large planar surface of go allows adsorption of different dna-agncs probes, each with a distinct emission, leading to a multicolor sensor for the detection of multiple dna targets in the same solution. |
| 收录类别 | SCI收录期刊论文 |
| 语种 | 英语 |
| WOS记录号 | WOS:000303768100011 |
| 公开日期 | 2013-06-30 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/48569]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Tao Y,Lin YH,Huang ZZ,et al. DNA-templated silver nanoclusters-graphene oxide nanohybrid materials: a platform for label-free and sensitive fluorescence turn-on detection of multiple nucleic acid targets[J]. analyst,2012,137(11):2588-2592. |
| APA | Tao Y,Lin YH,Huang ZZ,Ren JS,&Qu XG.(2012).DNA-templated silver nanoclusters-graphene oxide nanohybrid materials: a platform for label-free and sensitive fluorescence turn-on detection of multiple nucleic acid targets.analyst,137(11),2588-2592. |
| MLA | Tao Y,et al."DNA-templated silver nanoclusters-graphene oxide nanohybrid materials: a platform for label-free and sensitive fluorescence turn-on detection of multiple nucleic acid targets".analyst 137.11(2012):2588-2592. |
入库方式： OAI收割
来源：长春应用化学研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。