Functionalized mesoporous silica materials for controlled drug delivery
文献类型：期刊论文
| 作者 | Yang PP ; Gai SL ; Lin J |
| 刊名 | chemical society reviews
 |
| 出版日期 | 2012 |
| 卷号 | 41期号:9页码:3679-3698 |
| 关键词 | RESPONSIVE CONTROLLED-RELEASE UP-CONVERSION-LUMINESCENT OPERATED MECHANIZED NANOPARTICLES SHELL-STRUCTURED NANOCOMPOSITES SHAPE-CONTROLLED SYNTHESIS SIZE-CONTROLLED SYNTHESIS RARE-EARTH NANOPHOSPHORS QUANTUM DOTS IN-VIVO PORE-SIZE |
| ISSN号 | 0306-0012 |
| 通讯作者 | lin j |
| 中文摘要 | in the past decade, non-invasive and biocompatible mesoporous silica materials as efficient drug delivery systems have attracted special attention. great progress in structure control and functionalization (magnetism and luminescence) design has been achieved for biotechnological and biomedical applications. this review highlights the most recent research progress on silica-based controlled drug delivery systems, including: (i) pure mesoporous silica sustained-release systems, (ii) magnetism and/or luminescence functionalized mesoporous silica systems which integrate targeting and tracking abilities of drug molecules, and (iii) stimuli-responsive controlled release systems which are able to respond to environmental changes, such as ph, redox potential, temperature, photoirradiation, and biomolecules. although encouraging and potential developments have been achieved, design and mass production of novel multifunctional carriers, some practical biological application, such as biodistribution, the acute and chronic toxicities, long-term stability, circulation properties and targeting efficacy in vivo are still challenging. |
| 收录类别 | SCI收录期刊论文 |
| 语种 | 英语 |
| WOS记录号 | WOS:000302559700015 |
| 公开日期 | 2013-06-30 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/48582]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Yang PP,Gai SL,Lin J. Functionalized mesoporous silica materials for controlled drug delivery[J]. chemical society reviews,2012,41(9):3679-3698. |
| APA | Yang PP,Gai SL,&Lin J.(2012).Functionalized mesoporous silica materials for controlled drug delivery.chemical society reviews,41(9),3679-3698. |
| MLA | Yang PP,et al."Functionalized mesoporous silica materials for controlled drug delivery".chemical society reviews 41.9(2012):3679-3698. |
入库方式： OAI收割
来源：长春应用化学研究所
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