Uniform and size-tunable mesoporous silica with fibrous morphology for drug delivery
文献类型：期刊论文
| 作者 | Gai SL ; Yang PP ; Ma PA ; Wang LZ ; Li CX ; Zhang ML ; Jun L |
| 刊名 | dalton transactions
 |
| 出版日期 | 2012 |
| 卷号 | 41期号:15页码:4511-4516 |
| 关键词 | SUSTAINED-RELEASE PROPERTY LUMINESCENCE FUNCTIONALIZATION CARRIER SYSTEM NANOPARTICLES SPHERES IBUPROFEN SBA-15 NANOSPHERES YVO4-EU3+ MATRIX |
| ISSN号 | 1477-9226 |
| 通讯作者 | yang pp |
| 中文摘要 | a family of mesoporous silica microspheres with fibrous morphology and different particle sizes ranging from about 400 to 900 nm has been successfully synthesized through a facile self-assembly process. the structural, morphological, and textural properties of the samples were well characterized by scanning electron microscopy (sem), transmission electron microscopy (tem), nuclear magnetic resonance (nmr), fourier transform infrared spectroscopy (ft-ir), n-2 adsorption/desorption, and thermal gravimetry (tg). the results reveal that this silica-based mesoporous material exhibits excellent physical properties, including a fibrous spherical morphology, good thermal stability, large pore volume, high specific surface area and narrow size distribution. additionally, the size and textural properties can be tuned by altering the silica precursor/template molar ratio. the formation and the self-assembly evolution process have also been proposed. the obtained materials were further used as a drug delivery carrier to investigate the in vitro drug release properties using doxorubicin (dox) as a representative model drug. it was found that this kind of silica exhibits good biocompatibility and obvious sustained drug release properties, suggesting its potential application in biological fields. |
| 收录类别 | SCI收录期刊论文 |
| 语种 | 英语 |
| WOS记录号 | WOS:000301955900029 |
| 公开日期 | 2013-06-30 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/48584]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Gai SL,Yang PP,Ma PA,et al. Uniform and size-tunable mesoporous silica with fibrous morphology for drug delivery[J]. dalton transactions,2012,41(15):4511-4516. |
| APA | Gai SL.,Yang PP.,Ma PA.,Wang LZ.,Li CX.,...&Jun L.(2012).Uniform and size-tunable mesoporous silica with fibrous morphology for drug delivery.dalton transactions,41(15),4511-4516. |
| MLA | Gai SL,et al."Uniform and size-tunable mesoporous silica with fibrous morphology for drug delivery".dalton transactions 41.15(2012):4511-4516. |
入库方式： OAI收割
来源：长春应用化学研究所
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