DNA based identification of medicinal materials in Chinese patent medicines
文献类型：期刊论文
| 作者 | Chen, Rong ; Dong, Juan ; Cui, Xin ; Wang, Wei ; Yasmeen, Afshan ; Deng, Yun ; Zeng, Xiaomao ; Tang, Zhuo |
| 刊名 | SCIENTIFIC REPORTS
 |
| 出版日期 | 2012 |
| 卷号 | 2页码:- |
| ISSN号 | 2045-2322 |
| 产权排序 | 1 |
| 通讯作者 | Tang, Z (reprint author), Chinese Acad Sci, Chengdu Inst Biol, Nat Prod Res Ctr, Chengdu, Peoples R China ; Deng, Yun |
| 英文摘要 | Chinese patent medicines (CPM) are highly processed and easy to use Traditional Chinese Medicine (TCM). The market for CPM in China alone is tens of billions US dollars annually and some of the CPM are also used as dietary supplements for health augmentation in the western countries. But concerns continue to be raised about the legality, safety and efficacy of many popular CPM. Here we report a pioneer work of applying molecular biotechnology to the identification of CPM, particularly well refined oral liquids and injections. What's more, this PCR based method can also be developed to an easy to use and cost-effective visual chip by taking advantage of G-quadruplex based Hybridization Chain Reaction. This study demonstrates that DNA identification of specific Medicinal materials is an efficient and cost-effective way to audit highly processed CPM and will assist in monitoring their quality and legality. |
| 学科主题 | Science & Technology - Other Topics |
| 收录类别 | SCI |
| 资助信息 | Chinese Academy of Science (Hundreds of Talents Program); National Sciences Foundation of China [21172215, 21102140]; Innovation Program of the Chinese Academy of Sciences [KSCX2-EW-J-22]; Open Research Fund of State Key Laboratory Breeding Base of Systematic Research, Development and Utilization of Chinese Medicine Resource |
| 语种 | 英语 |
| WOS记录号 | WOS:000312274900007 |
| 公开日期 | 2013-07-03 |
| 源URL | [http://210.75.237.14/handle/351003/23871]  |
| 专题 | 成都生物研究所_天然产物研究 |
| 推荐引用方式 GB/T 7714 | Chen, Rong,Dong, Juan,Cui, Xin,et al. DNA based identification of medicinal materials in Chinese patent medicines[J]. SCIENTIFIC REPORTS,2012,2:-. |
| APA | Chen, Rong.,Dong, Juan.,Cui, Xin.,Wang, Wei.,Yasmeen, Afshan.,...&Tang, Zhuo.(2012).DNA based identification of medicinal materials in Chinese patent medicines.SCIENTIFIC REPORTS,2,-. |
| MLA | Chen, Rong,et al."DNA based identification of medicinal materials in Chinese patent medicines".SCIENTIFIC REPORTS 2(2012):-. |
入库方式： OAI收割
来源：成都生物研究所
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