A Facile One-Pot Process for the Formation of Hindered Tertiary Amines
文献类型：期刊论文
| 作者 | Wang, Zhouyu ; Pei, Dong ; Zhang, Yu ; Wang, Chao ; Sun, Jian |
| 刊名 | MOLECULES
 |
| 出版日期 | 2012 |
| 卷号 | 17期号:5页码:5151-5163 |
| 关键词 | reductive amination tertiary amine Lewis base trichlorosilane ketone |
| ISSN号 | 1420-3049 |
| 产权排序 | 2 |
| 通讯作者 | Wang, ZY (reprint author), Xihua Univ, Dept Pharmaceut Engn, Chengdu 610039, Peoples R China ; Sun, Jian |
| 英文摘要 | A simple and convenient method was developed for the preparation of hindered tertiary amines via direct reductive amination of ketones with secondary aryl amines, using trichlorosilane as reducing agent and tetramethylethylenediamine (TMEDA) as organic Lewis base activator. A broad range of ketones were reacted with N-methylaniline to afford the corresponding tertiary amine products in high yield. An open transition model was proposed for the reductive step. |
| 学科主题 | Chemistry |
| 收录类别 | SCI |
| 资助信息 | National Natural Science Foundation of China [21102115, 20972152, 91013006] |
| 语种 | 英语 |
| WOS记录号 | WOS:000304587600031 |
| 公开日期 | 2013-07-03 |
| 源URL | [http://210.75.237.14/handle/351003/23897]  |
| 专题 | 成都生物研究所_天然产物研究 |
| 推荐引用方式 GB/T 7714 | Wang, Zhouyu,Pei, Dong,Zhang, Yu,et al. A Facile One-Pot Process for the Formation of Hindered Tertiary Amines[J]. MOLECULES,2012,17(5):5151-5163. |
| APA | Wang, Zhouyu,Pei, Dong,Zhang, Yu,Wang, Chao,&Sun, Jian.(2012).A Facile One-Pot Process for the Formation of Hindered Tertiary Amines.MOLECULES,17(5),5151-5163. |
| MLA | Wang, Zhouyu,et al."A Facile One-Pot Process for the Formation of Hindered Tertiary Amines".MOLECULES 17.5(2012):5151-5163. |
入库方式： OAI收割
来源：成都生物研究所
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