A microfluidic origami chip for synthesis of functionalized polymeric nanoparticles
文献类型：期刊论文
| 作者 | Sun JS ; Xianyu YL; Li MM; Liu WW; Zhang L; Liu DB; Liu C(刘超); Hu GQ(胡国庆); Jiang XY
|
| 刊名 | NANOSCALE
 |
| 出版日期 | 2013-06-21 |
| 卷号 | 5期号:12页码:5262-5265 |
| 通讯作者邮箱 | xingyujiang@nanoctr.cn |
| 关键词 | Microfluidics - Nanoparticles - Synthesis (chemical) -- Cellular uptake - Functionalized - Mono-disperse - Poly lactic-co-glycolic acid - Polymeric nanoparticles - Three-dimensional designs |
| ISSN号 | 2040-3364 |
| 产权排序 | [Sun, Jiashu; Xianyu, Yunlei; Li, Mengmeng; Liu, Wenwen; Zhang, Lu; Liu, Dingbin; Jiang, Xingyu] Natl Ctr NanoSci & Technol, CAS Key Lab Biol Effects Nanomat & Nanosafety, Beijing 100190, Peoples R China; [Liu, Chao; Hu, Guoqing] Chinese Acad Sci, Inst Mech, LNM, Beijing 100190, Peoples R China |
| 通讯作者 | Jiang, XY (reprint author), Natl Ctr NanoSci & Technol, CAS Key Lab Biol Effects Nanomat & Nanosafety, Beijing 100190, Peoples R China. |
| 合作状况 | 国内 |
| 中文摘要 | This report demonstrates a microfluidic origami chip to synthesize monodisperse, doxorubicin-loaded poly(lactic-co-glycolic acid) nanoparticles with diameters of ～100 nm, a size optimized for cellular uptake and anticancer efficacy, but difficult to achieve with existing approaches. This three-dimensional design in a microchannel may allow for the fabrication of polymeric nanoparticles in this size regime with ease. |
| 学科主题 | 微机电系统中的流体力学问题 |
| 分类号 | 一类 |
| 收录类别 | SCI ; EI |
| 资助信息 | MOST [2009CB930001, 2011CB933201, 2012AA030308, 2011CB707604]; NSFC [51105086, 21025520, 51073045, 11272321]; CAS [KJCX2-YW-M15, KJCX2-YW-H18]; [SKLEAC201207] |
| 原文出处 | http://dx.doi.org/10.1039/c3nr01289a |
| 语种 | 英语 |
| WOS记录号 | WOS:000319756200011 |
| 公开日期 | 2013-08-12 |
| 源URL | [http://dspace.imech.ac.cn/handle/311007/47352]  |
| 专题 | 力学研究所_非线性力学国家重点实验室 |
| 推荐引用方式 GB/T 7714 | Sun JS,Xianyu YL,Li MM,et al. A microfluidic origami chip for synthesis of functionalized polymeric nanoparticles[J]. NANOSCALE,2013,5(12):5262-5265. |
| APA | Sun JS.,Xianyu YL.,Li MM.,Liu WW.,Zhang L.,...&Jiang XY.(2013).A microfluidic origami chip for synthesis of functionalized polymeric nanoparticles.NANOSCALE,5(12),5262-5265. |
| MLA | Sun JS,et al."A microfluidic origami chip for synthesis of functionalized polymeric nanoparticles".NANOSCALE 5.12(2013):5262-5265. |
入库方式： OAI收割
来源：力学研究所
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