Mass Spectrometry-Based Approach in Ginseng Research: A Promising Way to Metabolomics
文献类型：期刊论文
| 作者 | Wu W ; Song FR ; Guo DJ ; Mi J ; Qin QJ ; Yu Q ; Liu SY |
| 刊名 | current analytical chemistry
 |
| 出版日期 | 2012 |
| 卷号 | 8期号:1页码:43-66 |
| 关键词 | PERFORMANCE LIQUID-CHROMATOGRAPHY SOLID-PHASE EXTRACTION TRADITIONAL CHINESE MEDICINE STEAMED PANAX-NOTOGINSENG HUMAN BLOOD-PLASMA HPLC-ESI-MS ELECTROSPRAY-IONIZATION RAT PLASMA AMERICAN-GINSENG SYSTEMS BIOLOGY |
| ISSN号 | 1573-4110 |
| 通讯作者 | liu sy |
| 中文摘要 | this review summarizes the current status of mass spectrometry (ms)-based techniques used in ginseng research. the review has been explored from two parts. the first part presents an overview of the chemical analysis of ginseng based on ms and liquid chromatography-mass spectrometry (lc-ms), including the application of ms/ms on systematic structural characterization of ginsenosides and the fragmentation patterns of different metal adducts with ginsenoside for structure analysis, the characterization of ginsenosides in the crude extracts by lc-ms, the investigation of hydrolysis and changes of ginsenosides in ginseng and related prescription formula by lc-ms to provide the material basis for traditional chinese medicine (tcm), and pharmacokinetics and metabolism studies of ginsenosides by lc-ms. the second part focuses on the dynamically developing field of ms-based metabolomics and its potential applications in ginseng related research. this includes the strategy of ginseng quality control in terms of chemical changes for both original herbs and their processed products by plant metabolic profiling to ensure proper preparation and standardization, and the mechanism study and biomarker discovery for understanding the holistic effects and synergistic activities of ginseng. |
| 收录类别 | SCI收录期刊论文 |
| 语种 | 英语 |
| 公开日期 | 2013-08-25 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/48650]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Wu W,Song FR,Guo DJ,et al. Mass Spectrometry-Based Approach in Ginseng Research: A Promising Way to Metabolomics[J]. current analytical chemistry,2012,8(1):43-66. |
| APA | Wu W.,Song FR.,Guo DJ.,Mi J.,Qin QJ.,...&Liu SY.(2012).Mass Spectrometry-Based Approach in Ginseng Research: A Promising Way to Metabolomics.current analytical chemistry,8(1),43-66. |
| MLA | Wu W,et al."Mass Spectrometry-Based Approach in Ginseng Research: A Promising Way to Metabolomics".current analytical chemistry 8.1(2012):43-66. |
入库方式： OAI收割
来源：长春应用化学研究所
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