Controlled synthesis of luminescent F-substituted strontium hydroxyapatite with hierarchical structures for drug delivery
文献类型：期刊论文
| 作者 | Niu N ; Wang D ; Huang SH ; Li CX ; He F ; Gai SL ; Li XB ; Yang PP |
| 刊名 | crystengcomm
 |
| 出版日期 | 2012 |
| 卷号 | 14期号:5页码:1744-1752 |
| 关键词 | DOPED HYDROXYAPATITE HYDROTHERMAL METHOD CALCIUM-CARBONATE NANOSTRUCTURES COMBINATORIAL FLUORAPATITE NANOFIBERS PHOSPHORS EUROPIUM FUNCTIONALIZATION |
| ISSN号 | 1466-8033 |
| 通讯作者 | yang pp |
| 中文摘要 | fluorine substituted strontium hydroxyapatite doped with tb3+ or eu3+ ions (srfhap:ln) was successfully synthesized via an efficient and facile hydrothermal process using ethylene diamine tetraacetic acid disodium (na(2)edta) as the chelating ligand. the as-prepared srfhap:ln product was used as a drug carrier to investigate the drug storage and release properties using ibuprofen (ibu) as a model drug. x-ray diffraction (xrd), scanning electron microscopy (sem), transmission electron microscopy (tem), high-resolution transmission electron microscopy (hrtem), energy-dispersive x-ray spectrum (eds), x-ray photoelectron spectra (xps), fourier transform infrared spectroscopy (ft-ir), nitrogen adsorption/desorption, and photoluminescence spectra were employed to characterize the samples. the results reveal that the as-prepared fluorine substituted hydroxyapatites exhibit a hierarchical double-broccoli-like morphology. by tuning the ph value, na(2)edta content, and the reaction time, srfhap microstructures with different morphologies and sizes have been achieved. a possible formation process of these samples based on the crystal splitting growth mechanism has also been proposed in detail. moreover, the photoluminescence (pl) measurements indicate that the as-prepared srfhap:ln samples exhibit the characteristic emissions of tb3+ and eu3+ even after the loading of organic drug molecules, suggesting its feasible possibility to be monitored or tracked during the drug release and disease therapy process. |
| 收录类别 | SCI收录期刊论文 |
| 语种 | 英语 |
| WOS记录号 | WOS:000300045200035 |
| 公开日期 | 2013-08-29 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/48709]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Niu N,Wang D,Huang SH,et al. Controlled synthesis of luminescent F-substituted strontium hydroxyapatite with hierarchical structures for drug delivery[J]. crystengcomm,2012,14(5):1744-1752. |
| APA | Niu N.,Wang D.,Huang SH.,Li CX.,He F.,...&Yang PP.(2012).Controlled synthesis of luminescent F-substituted strontium hydroxyapatite with hierarchical structures for drug delivery.crystengcomm,14(5),1744-1752. |
| MLA | Niu N,et al."Controlled synthesis of luminescent F-substituted strontium hydroxyapatite with hierarchical structures for drug delivery".crystengcomm 14.5(2012):1744-1752. |
入库方式： OAI收割
来源：长春应用化学研究所
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