中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
ESIPT Fluorescence Probe Based on Double-Switch Recognition Mechanism for Selective and Rapid Detection of Hydrogen Sulfide in Living Cells

文献类型:期刊论文

作者Guan, Hongwei1; Zhang, Aixia2; Li, Peng3; Xia, Lixin2; Guo, Feng1
刊名ACS OMEGA
出版日期2019-05-01
卷号4期号:5页码:9113-9119
ISSN号2470-1343
DOI10.1021/acsomega.9b00934
通讯作者Xia, Lixin(lixinxia@lnu.edu.cn) ; Guo, Feng(0411guofeng@dlut.edu.cn)
英文摘要A novel fluorescence probe, HBTSeSe, was designed and synthesized for the detection of H2S with a double-switch mechanism of a broken diselenide bond followed by thiolysis of ether. Then, 2-(2'-hydroxyphenyl) benzothiazole (HBT) was released as fluorophore, which has large Stokes shift based on the excited state intramolecular proton transfer process. The probe responded selectively and rapidly to H2S, with the fluorescence increased by 47-fold immediately after the addition of H2S. HBTSeSe was able to detect H2S in the cytoplasm, specifically in cell imaging experiments. The results also showed that H2S was produced in the immune response of RAW264.7 cells activated by phorbol-12-myristate-13-acetate.
WOS关键词PROTON-TRANSFER ; SULFANE SULFUR ; SELENIUM ; H2S ; DISELENIDES ; BODIPY
资助项目China National Natural Science Foundation[31270620] ; China National Natural Science Foundation[21673237] ; Dalian Scientific and Technological Innovation Foundation[2018J12SN072]
WOS研究方向Chemistry
语种英语
WOS记录号WOS:000470094000134
出版者AMER CHEMICAL SOC
资助机构China National Natural Science Foundation ; China National Natural Science Foundation ; Dalian Scientific and Technological Innovation Foundation ; Dalian Scientific and Technological Innovation Foundation ; China National Natural Science Foundation ; China National Natural Science Foundation ; Dalian Scientific and Technological Innovation Foundation ; Dalian Scientific and Technological Innovation Foundation ; China National Natural Science Foundation ; China National Natural Science Foundation ; Dalian Scientific and Technological Innovation Foundation ; Dalian Scientific and Technological Innovation Foundation ; China National Natural Science Foundation ; China National Natural Science Foundation ; Dalian Scientific and Technological Innovation Foundation ; Dalian Scientific and Technological Innovation Foundation
源URL[http://cas-ir.dicp.ac.cn/handle/321008/172111]  
专题大连化学物理研究所_中国科学院大连化学物理研究所
通讯作者Xia, Lixin; Guo, Feng
作者单位1.Dalian Univ Technol, Sch Food & Environm, Minist Educ, Key Lab Ind Ecol & Environm Engn, Panjin 124000, Peoples R China
2.Liaoning Univ, Dept Chem, Shenyang 110036, Liaoning, Peoples R China
3.Chinese Acad Sci, DICP, State Key Lab Mol React Dynam, Dalian 116023, Peoples R China
推荐引用方式
GB/T 7714
Guan, Hongwei,Zhang, Aixia,Li, Peng,et al. ESIPT Fluorescence Probe Based on Double-Switch Recognition Mechanism for Selective and Rapid Detection of Hydrogen Sulfide in Living Cells[J]. ACS OMEGA,2019,4(5):9113-9119.
APA Guan, Hongwei,Zhang, Aixia,Li, Peng,Xia, Lixin,&Guo, Feng.(2019).ESIPT Fluorescence Probe Based on Double-Switch Recognition Mechanism for Selective and Rapid Detection of Hydrogen Sulfide in Living Cells.ACS OMEGA,4(5),9113-9119.
MLA Guan, Hongwei,et al."ESIPT Fluorescence Probe Based on Double-Switch Recognition Mechanism for Selective and Rapid Detection of Hydrogen Sulfide in Living Cells".ACS OMEGA 4.5(2019):9113-9119.

入库方式: OAI收割

来源:大连化学物理研究所

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