ESIPT Fluorescence Probe Based on Double-Switch Recognition Mechanism for Selective and Rapid Detection of Hydrogen Sulfide in Living Cells
文献类型:期刊论文
作者 | Guan, Hongwei1; Zhang, Aixia2; Li, Peng3; Xia, Lixin2; Guo, Feng1 |
刊名 | ACS OMEGA
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出版日期 | 2019-05-01 |
卷号 | 4期号:5页码:9113-9119 |
ISSN号 | 2470-1343 |
DOI | 10.1021/acsomega.9b00934 |
通讯作者 | Xia, Lixin(lixinxia@lnu.edu.cn) ; Guo, Feng(0411guofeng@dlut.edu.cn) |
英文摘要 | A novel fluorescence probe, HBTSeSe, was designed and synthesized for the detection of H2S with a double-switch mechanism of a broken diselenide bond followed by thiolysis of ether. Then, 2-(2'-hydroxyphenyl) benzothiazole (HBT) was released as fluorophore, which has large Stokes shift based on the excited state intramolecular proton transfer process. The probe responded selectively and rapidly to H2S, with the fluorescence increased by 47-fold immediately after the addition of H2S. HBTSeSe was able to detect H2S in the cytoplasm, specifically in cell imaging experiments. The results also showed that H2S was produced in the immune response of RAW264.7 cells activated by phorbol-12-myristate-13-acetate. |
WOS关键词 | PROTON-TRANSFER ; SULFANE SULFUR ; SELENIUM ; H2S ; DISELENIDES ; BODIPY |
资助项目 | China National Natural Science Foundation[31270620] ; China National Natural Science Foundation[21673237] ; Dalian Scientific and Technological Innovation Foundation[2018J12SN072] |
WOS研究方向 | Chemistry |
语种 | 英语 |
WOS记录号 | WOS:000470094000134 |
出版者 | AMER CHEMICAL SOC |
资助机构 | China National Natural Science Foundation ; China National Natural Science Foundation ; Dalian Scientific and Technological Innovation Foundation ; Dalian Scientific and Technological Innovation Foundation ; China National Natural Science Foundation ; China National Natural Science Foundation ; Dalian Scientific and Technological Innovation Foundation ; Dalian Scientific and Technological Innovation Foundation ; China National Natural Science Foundation ; China National Natural Science Foundation ; Dalian Scientific and Technological Innovation Foundation ; Dalian Scientific and Technological Innovation Foundation ; China National Natural Science Foundation ; China National Natural Science Foundation ; Dalian Scientific and Technological Innovation Foundation ; Dalian Scientific and Technological Innovation Foundation |
源URL | [http://cas-ir.dicp.ac.cn/handle/321008/172111] ![]() |
专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
通讯作者 | Xia, Lixin; Guo, Feng |
作者单位 | 1.Dalian Univ Technol, Sch Food & Environm, Minist Educ, Key Lab Ind Ecol & Environm Engn, Panjin 124000, Peoples R China 2.Liaoning Univ, Dept Chem, Shenyang 110036, Liaoning, Peoples R China 3.Chinese Acad Sci, DICP, State Key Lab Mol React Dynam, Dalian 116023, Peoples R China |
推荐引用方式 GB/T 7714 | Guan, Hongwei,Zhang, Aixia,Li, Peng,et al. ESIPT Fluorescence Probe Based on Double-Switch Recognition Mechanism for Selective and Rapid Detection of Hydrogen Sulfide in Living Cells[J]. ACS OMEGA,2019,4(5):9113-9119. |
APA | Guan, Hongwei,Zhang, Aixia,Li, Peng,Xia, Lixin,&Guo, Feng.(2019).ESIPT Fluorescence Probe Based on Double-Switch Recognition Mechanism for Selective and Rapid Detection of Hydrogen Sulfide in Living Cells.ACS OMEGA,4(5),9113-9119. |
MLA | Guan, Hongwei,et al."ESIPT Fluorescence Probe Based on Double-Switch Recognition Mechanism for Selective and Rapid Detection of Hydrogen Sulfide in Living Cells".ACS OMEGA 4.5(2019):9113-9119. |
入库方式: OAI收割
来源:大连化学物理研究所
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