Epitope Imprinting Technology: Progress, Applications, and Perspectives toward Artificial Antibodies
文献类型：期刊论文
| 作者 | Yang, Kaiguang2; Li, Senwu2; Liu, Lukuan2; Chen, Yuwan2; Zhou, Wen2; Pei, Jiaqi1,2; Liang, Zhen2; Zhang, Lihua2; Zhang, Yukui2 |
| 刊名 | ADVANCED MATERIALS
 |
| 出版日期 | 2019-08-18 |
| 页码 | 17 |
| ISSN号 | 0935-9648 |
| 关键词 | artificial antibodies epitopes molecular imprinting molecular recognition |
| DOI | 10.1002/adma.201902048 |
| 通讯作者 | Zhang, Lihua(lihuazhang@dicp.ac.cn) |
| 英文摘要 | Epitope imprinting is a promising tool to generate antibody-like specific recognition sites. Recently, because of the ease of obtaining templates, the flexibility in selecting monomers, their resistance to harsh environments, and the high specificity toward targets, epitope-imprinted materials have attracted much attention in various fields, such as bioanalysis, clinical therapy, and pharmacy. Here, the discussion is focused on the current representative epitope imprinting technologies, including epitope bulk imprinting and epitope surface imprinting. Moreover, the application of epitope-imprinted materials to the recognition of peptides, proteins, and cells is reviewed. Finally, the remaining challenges arising from the intrinsic properties of epitope imprinting are discussed, and future development in the field is prospected. |
| WOS关键词 | PROTEIN LYSINE ACETYLATION ; MASS-SPECTROMETRY ; IMMUNOGLOBULIN-G ; CANCER-CELLS ; HUMAN SERUM ; POLYMERS ; RECOGNITION ; AFFINITY ; NANOPARTICLES ; PURIFICATION |
| 资助项目 | National Key R&D Programme of China[2017YFA0505003] ; National Natural Science Foundation[21575143] ; National Natural Science Foundation[21725506] ; CAS Key Project in Frontier Science[QYZDY-SSW-SLH017] ; Innovation Programme of Science and Research from the DICP, CAS[DICP TMSR201601] |
| WOS研究方向 | Chemistry ; Science & Technology - Other Topics ; Materials Science ; Physics |
| 语种 | 英语 |
| 出版者 | WILEY-V C H VERLAG GMBH |
| WOS记录号 | WOS:000481819300001 |
| 资助机构 | National Key R&D Programme of China ; National Key R&D Programme of China ; National Natural Science Foundation ; National Natural Science Foundation ; CAS Key Project in Frontier Science ; CAS Key Project in Frontier Science ; Innovation Programme of Science and Research from the DICP, CAS ; Innovation Programme of Science and Research from the DICP, CAS ; National Key R&D Programme of China ; National Key R&D Programme of China ; National Natural Science Foundation ; National Natural Science Foundation ; CAS Key Project in Frontier Science ; CAS Key Project in Frontier Science ; Innovation Programme of Science and Research from the DICP, CAS ; Innovation Programme of Science and Research from the DICP, CAS ; National Key R&D Programme of China ; National Key R&D Programme of China ; National Natural Science Foundation ; National Natural Science Foundation ; CAS Key Project in Frontier Science ; CAS Key Project in Frontier Science ; Innovation Programme of Science and Research from the DICP, CAS ; Innovation Programme of Science and Research from the DICP, CAS ; National Key R&D Programme of China ; National Key R&D Programme of China ; National Natural Science Foundation ; National Natural Science Foundation ; CAS Key Project in Frontier Science ; CAS Key Project in Frontier Science ; Innovation Programme of Science and Research from the DICP, CAS ; Innovation Programme of Science and Research from the DICP, CAS |
| 源URL | [http://cas-ir.dicp.ac.cn/handle/321008/173531]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 通讯作者 | Zhang, Lihua |
| 作者单位 | 1.Dalian Univ Technol, Zhang Dayu Sch Chem, Dalian 116024, Peoples R China 2.Chinese Acad Sci, CAS Key Lab Separat Sci Analyt Chem, Dalian Inst Chem Phys, Dalian 116023, Peoples R China |
| 推荐引用方式 GB/T 7714 | Yang, Kaiguang,Li, Senwu,Liu, Lukuan,et al. Epitope Imprinting Technology: Progress, Applications, and Perspectives toward Artificial Antibodies[J]. ADVANCED MATERIALS,2019:17. |
| APA | Yang, Kaiguang.,Li, Senwu.,Liu, Lukuan.,Chen, Yuwan.,Zhou, Wen.,...&Zhang, Yukui.(2019).Epitope Imprinting Technology: Progress, Applications, and Perspectives toward Artificial Antibodies.ADVANCED MATERIALS,17. |
| MLA | Yang, Kaiguang,et al."Epitope Imprinting Technology: Progress, Applications, and Perspectives toward Artificial Antibodies".ADVANCED MATERIALS (2019):17. |
入库方式： OAI收割
来源：大连化学物理研究所
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