Metal-free synthesis of gem-silylboronate esters and their Pd(0)-catalyzed cross-coupling with aryliodides
文献类型：期刊论文
| 作者 | Wu, Chaoqiang1; Bao, Zhicheng1; Xu, Xing1; Wang, Jianbo1,2 |
| 刊名 | ORGANIC & BIOMOLECULAR CHEMISTRY
 |
| 出版日期 | 2019-06-21 |
| 卷号 | 17期号:23页码:5714-5724 |
| ISSN号 | 1477-0520 |
| DOI | 10.1039/c9ob01006h |
| 通讯作者 | Wang, Jianbo(wangjb@pku.edu.cn) |
| 英文摘要 | A transition-metal-free method for the synthesis of gem-silylboronate esters with arylboronic acids and trimethylsilyldiazomethane (TMSCHN2) has been developed. This transformation is a straightforward homologation of arylboronic acids and features wide substrate scope and good functional-group tolerance. The gem-silylboronate esters undergo efficient Suzuki-Miyaura cross-coupling with aryliodides and the silyl group of the product can be further functionalized. Tertiary carbon centers with different substituents can be constructed successfully by selective and sequential functionalization. |
| WOS关键词 | ENANTIOSELECTIVE SYNTHESIS ; 1,1-DIBORONATE ESTERS ; DIAZO-COMPOUNDS ; CARBON ; BOND ; ARYL ; 1,1-DIBORYLALKANES ; DIBORYLMETHANE ; HYDROBORATION ; REAGENTS |
| 资助项目 | National Natural Science Foundation of China[21871010] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000475704000011 |
| 出版者 | ROYAL SOC CHEMISTRY |
| 资助机构 | National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China |
| 源URL | [http://cas-ir.dicp.ac.cn/handle/321008/173985]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 通讯作者 | Wang, Jianbo |
| 作者单位 | 1.Peking Univ, Key Lab Bioorgan Chem & Mol Engn, BNLMS, Minist Educ,Coll Chem, Beijing 100871, Peoples R China 2.Chinese Acad Sci, State Key Lab Organometall Chem, Shanghai 200032, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wu, Chaoqiang,Bao, Zhicheng,Xu, Xing,et al. Metal-free synthesis of gem-silylboronate esters and their Pd(0)-catalyzed cross-coupling with aryliodides[J]. ORGANIC & BIOMOLECULAR CHEMISTRY,2019,17(23):5714-5724. |
| APA | Wu, Chaoqiang,Bao, Zhicheng,Xu, Xing,&Wang, Jianbo.(2019).Metal-free synthesis of gem-silylboronate esters and their Pd(0)-catalyzed cross-coupling with aryliodides.ORGANIC & BIOMOLECULAR CHEMISTRY,17(23),5714-5724. |
| MLA | Wu, Chaoqiang,et al."Metal-free synthesis of gem-silylboronate esters and their Pd(0)-catalyzed cross-coupling with aryliodides".ORGANIC & BIOMOLECULAR CHEMISTRY 17.23(2019):5714-5724. |
入库方式： OAI收割
来源：大连化学物理研究所
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