synthesisofnadanalogstodevelopbioorthogonalredoxsystem
文献类型：期刊论文
| 作者 | Ji Debin; Wang Lei; Liu Wujun; Hou Shuhua; Zhao Zongbao K |
| 刊名 | sciencechinachemistry
 |
| 出版日期 | 2013-01-01 |
| 卷号 | 56期号:3页码:296 |
| ISSN号 | 1674-7291 |
| 英文摘要 | Three new nicotinamide adenine dinucleotide(NAD) analogs were synthesized, and their characteristics as cofactors for Escherichia coli malic enzyme(ME) and its double mutant ME L310R/Q401C were analyzed.Each pair of the NAD analog and the double mutant showed good orthogonality to the natural pair of NAD and ME in terms of catalyzing oxidative decarboxylation of L-malic acid.Results indicated that molecular interactions between redox enzyme and cofactor could be further explored to generate new bioorthogonal redox systems. |
| 语种 | 英语 |
| 源URL | [http://cas-ir.dicp.ac.cn/handle/321008/178419]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | 中国科学院大连化学物理研究所 |
| 推荐引用方式 GB/T 7714 | Ji Debin,Wang Lei,Liu Wujun,et al. synthesisofnadanalogstodevelopbioorthogonalredoxsystem[J]. sciencechinachemistry,2013,56(3):296. |
| APA | Ji Debin,Wang Lei,Liu Wujun,Hou Shuhua,&Zhao Zongbao K.(2013).synthesisofnadanalogstodevelopbioorthogonalredoxsystem.sciencechinachemistry,56(3),296. |
| MLA | Ji Debin,et al."synthesisofnadanalogstodevelopbioorthogonalredoxsystem".sciencechinachemistry 56.3(2013):296. |
入库方式： OAI收割
来源：大连化学物理研究所
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