A Novel Solution-auto-introduction Electrophoresis Microchip Based on Capillary Force
文献类型：期刊论文
| 作者 | Yang, Mingpeng1,2; Huang, Zhe1,2; Chang, Jianguo1,2; You, Hui1,2
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| 刊名 | ANALYTICAL SCIENCES
 |
| 出版日期 | 2018-11-01 |
| 卷号 | 34期号:11页码:1285-1290 |
| 关键词 | Electrophoresis microchip solution-auto-introduction suction materials |
| ISSN号 | 0910-6340 |
| 通讯作者 | You, Hui(usmlhy@iim.ac.cn) |
| 英文摘要 | A novel solution-auto-introduction electrophoresis microchip based on capillary force aimed at improving portability is proposed in this paper. Two kinds of materials with micropores, poly(vinyl alcohol) (PVA)-sponge and nano-sponge, were employed as suction pumps that realized the introduction of a running buffer into the reservoirs. The surfaces of the microchannels in the microchips were modified by PVA to improve the moving velocity of the running buffer and the detection performance of the microchip. The introduction velocity of a running buffer in the PVA-coated microchannels was increased by two times compared with that in the native microchannels. The electrophoresis detection performance of several microchips composed of different microchannels and suction materials were evaluated comparatively. The results indicated that the surface coating of PVA can significantly improve the repeatability of the detection results by 20 - 40%, and the noise of the detected signals in the PVA-coated microchips is much lower than that in the native microchips. The proposed solution-auto-introduction electrophoresis microchip is a successful attempt that completely avoids the external connectors to accomplish the auto-introduction of running buffer. The solution-auto-introduction method provides a new train of thought for portable detection instruments with electrophoresis microchips in the future. |
| WOS关键词 | CONTACTLESS CONDUCTIVITY DETECTOR ; LARGE-VOLUME SAMPLE ; INJECTION ; DRIVEN ; DEVICE |
| 资助项目 | National Key Technology Research and Development Program of the Ministry of Science and Technology of China[SQ2015BA0800060] ; Science and Technology Research Project of Anhui Province, China[1501031088] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000452249300011 |
| 出版者 | JAPAN SOC ANALYTICAL CHEMISTRY |
| 资助机构 | National Key Technology Research and Development Program of the Ministry of Science and Technology of China ; National Key Technology Research and Development Program of the Ministry of Science and Technology of China ; National Key Technology Research and Development Program of the Ministry of Science and Technology of China ; National Key Technology Research and Development Program of the Ministry of Science and Technology of China ; Science and Technology Research Project of Anhui Province, China ; Science and Technology Research Project of Anhui Province, China ; Science and Technology Research Project of Anhui Province, China ; Science and Technology Research Project of Anhui Province, China ; National Key Technology Research and Development Program of the Ministry of Science and Technology of China ; National Key Technology Research and Development Program of the Ministry of Science and Technology of China ; National Key Technology Research and Development Program of the Ministry of Science and Technology of China ; National Key Technology Research and Development Program of the Ministry of Science and Technology of China ; Science and Technology Research Project of Anhui Province, China ; Science and Technology Research Project of Anhui Province, China ; Science and Technology Research Project of Anhui Province, China ; Science and Technology Research Project of Anhui Province, China ; National Key Technology Research and Development Program of the Ministry of Science and Technology of China ; National Key Technology Research and Development Program of the Ministry of Science and Technology of China ; National Key Technology Research and Development Program of the Ministry of Science and Technology of China ; National Key Technology Research and Development Program of the Ministry of Science and Technology of China ; Science and Technology Research Project of Anhui Province, China ; Science and Technology Research Project of Anhui Province, China ; Science and Technology Research Project of Anhui Province, China ; Science and Technology Research Project of Anhui Province, China ; National Key Technology Research and Development Program of the Ministry of Science and Technology of China ; National Key Technology Research and Development Program of the Ministry of Science and Technology of China ; National Key Technology Research and Development Program of the Ministry of Science and Technology of China ; National Key Technology Research and Development Program of the Ministry of Science and Technology of China ; Science and Technology Research Project of Anhui Province, China ; Science and Technology Research Project of Anhui Province, China ; Science and Technology Research Project of Anhui Province, China ; Science and Technology Research Project of Anhui Province, China |
| 源URL | [http://ir.hfcas.ac.cn:8080/handle/334002/41131]  |
| 专题 | 合肥物质科学研究院_中科院合肥智能机械研究所 |
| 通讯作者 | You, Hui |
| 作者单位 | 1.Chinese Acad Sci, Inst Intelligent Machines, Hefei 23003, Anhui, Peoples R China 2.Univ Sci & Technol China, Hefei 230026, Anhui, Peoples R China |
| 推荐引用方式 GB/T 7714 | Yang, Mingpeng,Huang, Zhe,Chang, Jianguo,et al. A Novel Solution-auto-introduction Electrophoresis Microchip Based on Capillary Force[J]. ANALYTICAL SCIENCES,2018,34(11):1285-1290. |
| APA | Yang, Mingpeng,Huang, Zhe,Chang, Jianguo,&You, Hui.(2018).A Novel Solution-auto-introduction Electrophoresis Microchip Based on Capillary Force.ANALYTICAL SCIENCES,34(11),1285-1290. |
| MLA | Yang, Mingpeng,et al."A Novel Solution-auto-introduction Electrophoresis Microchip Based on Capillary Force".ANALYTICAL SCIENCES 34.11(2018):1285-1290. |
入库方式： OAI收割
来源：合肥物质科学研究院
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