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  4. 技术生物与农业工程研究所
Quercetin potentiates the concurrent hyper-accumulation of cellular biomass and lipids in Chlorella vulgaris

文献类型：期刊论文

作者Ma, Yuhan1; Balamurugan, Srinivasan2; Yuan, Wasiqi2; Yang, Fan3; Tang, Caiguo1; Hu, Hao1; Zhang, Huilan1; Shu, Xian1; Li, Minghao1; Huang, Shengwei1
刊名BIORESOURCE TECHNOLOGY
出版日期2018-12-01
卷号269页码:434-442
关键词Chlorella vulgaris Quercetin Chemical modulator Biomass Lipid
ISSN号0960-8524
DOI10.1016/j.biortech.2018.07.151
通讯作者Wu, Lifang(lfwu@ipp.ac.cn)
英文摘要Provision of chemical modulators has emerged as an effective strategy to govern cell growth and development. Here, the impact of flavonoid quercetin on algal growth, lipid accumulation and transcriptional patterns was investigated in the green microalga Chlorella vulgaris. These results demonstrated that quercetin (15 mu g/l) significantly enhanced the cellular biomass and photosynthetic efficiency, with up to 2.5-fold in the biomass in the stationary phase. Lipidomic analyses revealed that lipid content was increased by 1.8-fold. Furthermore, the functional mechanism of quercetin on the molecular level was dissected by transcriptomic analysis. Results revealed that quercetin upregulated the expression pattern of key genes involved in cellular signaling mechanisms such as phosphatidylinositol 4-kinase alpha, thus consequently enhanced cell growth. Altogether, the data present in this study demonstrate the dramatic role of quercetin on enhancing microalgal biomass and lipid accumulation by unprecedented regulation, of key metabolic nodes, for the first time and provide a novel insight into microalgal metabolism and regulation.
WOS关键词TRANSGENIC ARABIDOPSIS-THALIANA ; STRESS TOLERANCE ; GENE-EXPRESSION ; ABIOTIC STRESS ; PLANTS ; FLAVONOIDS ; PRODUCTIVITY ; PYRENOIDOSA ; METABOLISM ; PATHWAYS
资助项目National Natural Science Foundation of China, China[31500531] ; Chinese Academy of Sciences, China[KFJ-STS-ZDTP-002] ; key program of 13th five-year plan, CASHIPS, China[kp-2017-21] ; President Foundation of Hefei Institutes of Physical Science of Chinese Academy of Sciences, China[YZJJ201619] ; major special project of Anhui Province, China[16030701103] ; Natural Science Foundation of Anhui province, China[1708085QC70] ; Natural Science Foundation of Anhui province, China[1808085QC73]
WOS研究方向Agriculture ; Biotechnology & Applied Microbiology ; Energy & Fuels
语种英语
WOS记录号WOS:000445897400053
出版者ELSEVIER SCI LTD
资助机构National Natural Science Foundation of China, China ; National Natural Science Foundation of China, China ; National Natural Science Foundation of China, China ; National Natural Science Foundation of China, China ; Chinese Academy of Sciences, China ; Chinese Academy of Sciences, China ; Chinese Academy of Sciences, China ; Chinese Academy of Sciences, China ; key program of 13th five-year plan, CASHIPS, China ; key program of 13th five-year plan, CASHIPS, China ; key program of 13th five-year plan, CASHIPS, China ; key program of 13th five-year plan, CASHIPS, China ; President Foundation of Hefei Institutes of Physical Science of Chinese Academy of Sciences, China ; President Foundation of Hefei Institutes of Physical Science of Chinese Academy of Sciences, China ; President Foundation of Hefei Institutes of Physical Science of Chinese Academy of Sciences, China ; President Foundation of Hefei Institutes of Physical Science of Chinese Academy of Sciences, China ; major special project of Anhui Province, China ; major special project of Anhui Province, China ; major special project of Anhui Province, China ; major special project of Anhui Province, China ; Natural Science Foundation of Anhui province, China ; Natural Science Foundation of Anhui province, China ; Natural Science Foundation of Anhui province, China ; Natural Science Foundation of Anhui province, China ; National Natural Science Foundation of China, China ; National Natural Science Foundation of China, China ; National Natural Science Foundation of China, China ; National Natural Science Foundation of China, China ; Chinese Academy of Sciences, China ; Chinese Academy of Sciences, China ; Chinese Academy of Sciences, China ; Chinese Academy of Sciences, China ; key program of 13th five-year plan, CASHIPS, China ; key program of 13th five-year plan, CASHIPS, China ; key program of 13th five-year plan, CASHIPS, China ; key program of 13th five-year plan, CASHIPS, China ; President Foundation of Hefei Institutes of Physical Science of Chinese Academy of Sciences, China ; President Foundation of Hefei Institutes of Physical Science of Chinese Academy of Sciences, China ; President Foundation of Hefei Institutes of Physical Science of Chinese Academy of Sciences, China ; President Foundation of Hefei Institutes of Physical Science of Chinese Academy of Sciences, China ; major special project of Anhui Province, China ; major special project of Anhui Province, China ; major special project of Anhui Province, China ; major special project of Anhui Province, China ; Natural Science Foundation of Anhui province, China ; Natural Science Foundation of Anhui province, China ; Natural Science Foundation of Anhui province, China ; Natural Science Foundation of Anhui province, China ; National Natural Science Foundation of China, China ; National Natural Science Foundation of China, China ; National Natural Science Foundation of China, China ; National Natural Science Foundation of China, China ; Chinese Academy of Sciences, China ; Chinese Academy of Sciences, China ; Chinese Academy of Sciences, China ; Chinese Academy of Sciences, China ; key program of 13th five-year plan, CASHIPS, China ; key program of 13th five-year plan, CASHIPS, China ; key program of 13th five-year plan, CASHIPS, China ; key program of 13th five-year plan, CASHIPS, China ; President Foundation of Hefei Institutes of Physical Science of Chinese Academy of Sciences, China ; President Foundation of Hefei Institutes of Physical Science of Chinese Academy of Sciences, China ; President Foundation of Hefei Institutes of Physical Science of Chinese Academy of Sciences, China ; President Foundation of Hefei Institutes of Physical Science of Chinese Academy of Sciences, China ; major special project of Anhui Province, China ; major special project of Anhui Province, China ; major special project of Anhui Province, China ; major special project of Anhui Province, China ; Natural Science Foundation of Anhui province, China ; Natural Science Foundation of Anhui province, China ; Natural Science Foundation of Anhui province, China ; Natural Science Foundation of Anhui province, China ; National Natural Science Foundation of China, China ; National Natural Science Foundation of China, China ; National Natural Science Foundation of China, China ; National Natural Science Foundation of China, China ; Chinese Academy of Sciences, China ; Chinese Academy of Sciences, China ; Chinese Academy of Sciences, China ; Chinese Academy of Sciences, China ; key program of 13th five-year plan, CASHIPS, China ; key program of 13th five-year plan, CASHIPS, China ; key program of 13th five-year plan, CASHIPS, China ; key program of 13th five-year plan, CASHIPS, China ; President Foundation of Hefei Institutes of Physical Science of Chinese Academy of Sciences, China ; President Foundation of Hefei Institutes of Physical Science of Chinese Academy of Sciences, China ; President Foundation of Hefei Institutes of Physical Science of Chinese Academy of Sciences, China ; President Foundation of Hefei Institutes of Physical Science of Chinese Academy of Sciences, China ; major special project of Anhui Province, China ; major special project of Anhui Province, China ; major special project of Anhui Province, China ; major special project of Anhui Province, China ; Natural Science Foundation of Anhui province, China ; Natural Science Foundation of Anhui province, China ; Natural Science Foundation of Anhui province, China ; Natural Science Foundation of Anhui province, China
源URL[http://ir.hfcas.ac.cn:8080/handle/334002/39271]  
专题合肥物质科学研究院_技术生物与农业工程研究所
通讯作者Wu, Lifang
作者单位1.Chinese Acad Sci, Hefei Inst Phys Sci, Key Lab High Magnet Field & Ion Beam Phys Biol, 350 Shushanhu Rd, Hefei 230031, Anhui, Peoples R China
2.Jinan Univ, Coll Life Sci, Key Lab Eutrophicat & Red Tide Prevent, Guangdong Higher Educ Inst, Guangzhou 510632, Guangdong, Peoples R China
3.Anhui Agr Univ, Sch Forestry & Landscape Architecture, Hefei 230031, Anhui, Peoples R China
推荐引用方式
GB/T 7714		 Ma, Yuhan,Balamurugan, Srinivasan,Yuan, Wasiqi,et al. Quercetin potentiates the concurrent hyper-accumulation of cellular biomass and lipids in Chlorella vulgaris[J]. BIORESOURCE TECHNOLOGY,2018,269:434-442.
APA Ma, Yuhan.,Balamurugan, Srinivasan.,Yuan, Wasiqi.,Yang, Fan.,Tang, Caiguo.,...&Wu, Lifang.(2018).Quercetin potentiates the concurrent hyper-accumulation of cellular biomass and lipids in Chlorella vulgaris.BIORESOURCE TECHNOLOGY,269,434-442.
MLA Ma, Yuhan,et al."Quercetin potentiates the concurrent hyper-accumulation of cellular biomass and lipids in Chlorella vulgaris".BIORESOURCE TECHNOLOGY 269(2018):434-442.

入库方式： OAI收割

来源：合肥物质科学研究院

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