Au(I)-Catalyzed Intramolecular Hydroamination of the Fluorinated N '-Aryl-N-Propargyl Amidines: Mild Conditions for the Synthesis of 2-Fluoroalkyl Imidazole Derivatives
文献类型：期刊论文
| 作者 | Li S(李珊) ; Li ZK(李正珂) ; Yuan YF(袁亚芬) ; Peng DJ(彭东杰) ; Li YJ(李亚军) ; Zhang LS(张里斯) ; Wu YM(吴永明) |
| 刊名 | Org. Lett.
 |
| 出版日期 | 2012 |
| 卷号 | 14期号:4页码:1130-1133 |
| ISSN号 | 1523-7060 |
| 其他题名 | 一价金催化的含氟N-芳基-N'-炔基脒类化合物的分子内胺氢化反应: 一种合成2-氟烷基取代的咪唑衍生物的简便方法 |
| 通讯作者 | 吴永明 |
| 英文摘要 | The gold(I)-catalyzed synthesis of 2-fluoroalkyl imidazole derivatives was developed. Catalyzed by gold(I), propargyl amidines underwent a 5-exo-dig cyclization to afford 2-fluoroalkyl-5-methyl imidazoles. Also, 2-fluoroalkyl imidazole-5-carbaldehydes were obtained in the presence of NIS. A mechanism investigation manifested the probable process and the carbonyl oxygen derived from O-2. |
| 学科主题 | 氟化学 |
| 收录类别 | SCI |
| 原文出处 | http://dx.doi.org/10.1021/ol3000525 |
| 语种 | 英语 |
| WOS记录号 | WOS:000300339800045 |
| 公开日期 | 2013-08-23 |
| 源URL | [http://202.127.28.38/handle/331003/28281]  |
| 专题 | 上海有机化学研究所_中科院有机氟化学重点实验室 |
| 推荐引用方式 GB/T 7714 | Li S,Li ZK,Yuan YF,et al. Au(I)-Catalyzed Intramolecular Hydroamination of the Fluorinated N '-Aryl-N-Propargyl Amidines: Mild Conditions for the Synthesis of 2-Fluoroalkyl Imidazole Derivatives[J]. Org. Lett.,2012,14(4):1130-1133. |
| APA | 李珊.,李正珂.,袁亚芬.,彭东杰.,李亚军.,...&吴永明.(2012).Au(I)-Catalyzed Intramolecular Hydroamination of the Fluorinated N '-Aryl-N-Propargyl Amidines: Mild Conditions for the Synthesis of 2-Fluoroalkyl Imidazole Derivatives.Org. Lett.,14(4),1130-1133. |
| MLA | 李珊,et al."Au(I)-Catalyzed Intramolecular Hydroamination of the Fluorinated N '-Aryl-N-Propargyl Amidines: Mild Conditions for the Synthesis of 2-Fluoroalkyl Imidazole Derivatives".Org. Lett. 14.4(2012):1130-1133. |
入库方式： OAI收割
来源：上海有机化学研究所
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