A facile preparation of 2-bromodifluoromethyl benzo-1,3-diazoles and its application in the synthesis of gem-difluoromethylene linked aryl ether compounds
文献类型：期刊论文
| 作者 | Jiang HZ(蒋海珍) ; Yuan SJ(袁世杰) ; Cai YS(蔡叶山) ; Wan W(万文) ; Zhu SZ(朱仕正) ; Hao J(郝建) |
| 刊名 | J. Fluor. Chem.
 |
| 出版日期 | 2012 |
| 卷号 | 133页码:167-170 |
| ISSN号 | 0022-1139 |
| 其他题名 | 2-溴二氟亚甲基苯并二唑类化合物的简便合成以及其在偕二氟亚甲基串联芳基醚化合物合成中的应用 |
| 通讯作者 | 朱仕正 ; 郝建 |
| 英文摘要 | A facile preparation of 2-bromodifluoromethyl benzo-1,3-diazoles as novel CF2Br-containing heterocyclic building blocks has been developed through a one-pot process of reaction of 2-OH, 2-SH, or 2-NH2 substituted aniline with bromodifluoroacetic acid in the presence of 3 molar equivalents of CBR4 and Ph3P in refluxing toluene. 2-Bromodifluoromethyl benzo-1,3-thiazole (2b) was successfully utilized in the preparation of gem-difluoromethylene linked aryl ether compounds through the reaction with phenolates or thiophenolate in DMF in good yields. (C) 2011 Elsevier B.V. All rights reserved. |
| 学科主题 | 氟化学 |
| 收录类别 | SCI |
| 原文出处 | http://dx.doi.org/10.1016/j.jfluchem.2011.08.008 |
| 语种 | 英语 |
| WOS记录号 | WOS:000300469500026 |
| 公开日期 | 2013-08-23 |
| 源URL | [http://202.127.28.38/handle/331003/28311]  |
| 专题 | 上海有机化学研究所_中科院有机氟化学重点实验室 |
| 推荐引用方式 GB/T 7714 | Jiang HZ,Yuan SJ,Cai YS,et al. A facile preparation of 2-bromodifluoromethyl benzo-1,3-diazoles and its application in the synthesis of gem-difluoromethylene linked aryl ether compounds[J]. J. Fluor. Chem.,2012,133:167-170. |
| APA | 蒋海珍,袁世杰,蔡叶山,万文,朱仕正,&郝建.(2012).A facile preparation of 2-bromodifluoromethyl benzo-1,3-diazoles and its application in the synthesis of gem-difluoromethylene linked aryl ether compounds.J. Fluor. Chem.,133,167-170. |
| MLA | 蒋海珍,et al."A facile preparation of 2-bromodifluoromethyl benzo-1,3-diazoles and its application in the synthesis of gem-difluoromethylene linked aryl ether compounds".J. Fluor. Chem. 133(2012):167-170. |
入库方式： OAI收割
来源：上海有机化学研究所
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