A 1,4-Diphenyl-1,2,3-Triazole-Based beta-Turn Mimic Constructed by Click Chemistry
文献类型:期刊论文
作者 | Wu CF(吴春芳) ; Zhao X(赵新) ; Lan WX(蓝文贤) ; Cao CY(曹春阳) ; Liu JT(刘金涛) ; Jiang XK(蒋锡夔) ; Li ZT(黎占亭) |
刊名 | J. Org. Chem.
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出版日期 | 2012 |
卷号 | 77期号:9页码:4261-4270 |
ISSN号 | 0022-3263 |
其他题名 | 点击化学构筑一种基于1,3-二苯基1,2,3-三氮唑的β-转角模拟结构 |
通讯作者 | 赵新 ; 黎占亭 |
英文摘要 | A series of 1,4-diphenyl-1,2,3-triazole-incorporated amide derivatives have been designed and prepared. Xray crystallographic and (1D and 2D) 1H NMR studies reveal that these compounds fold into stable U-shaped conformations driven by three-center intramolecular C-H center dot center dot center dot O hydrogen-bonding formed between the triazole C-5 H atom and the two ether O atoms. Such folded structures make this 1,4-diphenyl-1,2,3-triazole skeleton a good candidate to be used as beta-turn mimic. To prove this, the formation of a beta-hairpin structure induced by this beta-turn motif has been further demonstrated. |
学科主题 | 物理有机化学 |
收录类别 | SCI |
原文出处 | http://dx.doi.org/10.1021/jo300063u |
语种 | 英语 |
WOS记录号 | WOS:000303492300009 |
公开日期 | 2013-08-29 |
源URL | [http://202.127.28.38/handle/331003/28699] ![]() |
专题 | 上海有机化学研究所_物理有机化学研究室 |
推荐引用方式 GB/T 7714 | Wu CF,Zhao X,Lan WX,et al. A 1,4-Diphenyl-1,2,3-Triazole-Based beta-Turn Mimic Constructed by Click Chemistry[J]. J. Org. Chem.,2012,77(9):4261-4270. |
APA | 吴春芳.,赵新.,蓝文贤.,曹春阳.,刘金涛.,...&黎占亭.(2012).A 1,4-Diphenyl-1,2,3-Triazole-Based beta-Turn Mimic Constructed by Click Chemistry.J. Org. Chem.,77(9),4261-4270. |
MLA | 吴春芳,et al."A 1,4-Diphenyl-1,2,3-Triazole-Based beta-Turn Mimic Constructed by Click Chemistry".J. Org. Chem. 77.9(2012):4261-4270. |
入库方式: OAI收割
来源:上海有机化学研究所
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