中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
A 1,4-Diphenyl-1,2,3-Triazole-Based beta-Turn Mimic Constructed by Click Chemistry

文献类型:期刊论文

作者Wu CF(吴春芳) ; Zhao X(赵新) ; Lan WX(蓝文贤) ; Cao CY(曹春阳) ; Liu JT(刘金涛) ; Jiang XK(蒋锡夔) ; Li ZT(黎占亭)
刊名J. Org. Chem.
出版日期2012
卷号77期号:9页码:4261-4270
ISSN号0022-3263
其他题名点击化学构筑一种基于1,3-二苯基1,2,3-三氮唑的β-转角模拟结构
通讯作者赵新 ; 黎占亭
英文摘要A series of 1,4-diphenyl-1,2,3-triazole-incorporated amide derivatives have been designed and prepared. Xray crystallographic and (1D and 2D) 1H NMR studies reveal that these compounds fold into stable U-shaped conformations driven by three-center intramolecular C-H center dot center dot center dot O hydrogen-bonding formed between the triazole C-5 H atom and the two ether O atoms. Such folded structures make this 1,4-diphenyl-1,2,3-triazole skeleton a good candidate to be used as beta-turn mimic. To prove this, the formation of a beta-hairpin structure induced by this beta-turn motif has been further demonstrated.
学科主题物理有机化学
收录类别SCI
原文出处http://dx.doi.org/10.1021/jo300063u
语种英语
WOS记录号WOS:000303492300009
公开日期2013-08-29
源URL[http://202.127.28.38/handle/331003/28699]  
专题上海有机化学研究所_物理有机化学研究室
推荐引用方式
GB/T 7714
Wu CF,Zhao X,Lan WX,et al. A 1,4-Diphenyl-1,2,3-Triazole-Based beta-Turn Mimic Constructed by Click Chemistry[J]. J. Org. Chem.,2012,77(9):4261-4270.
APA 吴春芳.,赵新.,蓝文贤.,曹春阳.,刘金涛.,...&黎占亭.(2012).A 1,4-Diphenyl-1,2,3-Triazole-Based beta-Turn Mimic Constructed by Click Chemistry.J. Org. Chem.,77(9),4261-4270.
MLA 吴春芳,et al."A 1,4-Diphenyl-1,2,3-Triazole-Based beta-Turn Mimic Constructed by Click Chemistry".J. Org. Chem. 77.9(2012):4261-4270.

入库方式: OAI收割

来源:上海有机化学研究所

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