中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
A simple selective protocol for continuous two-stage fluorescent sensing of both MeHg+ and anti-MeHg+ agents in living cells

文献类型:期刊论文

作者Mei DS(梅德盛) ; He BK(何宝坤) ; Chen L(陈磊) ; Yao ZJ(姚祝军)
刊名Tetrahedron Lett.
出版日期2012
卷号53期号:27页码:3463-3466
ISSN号0040-4039
其他题名在活细胞中连续两个阶段荧光检测甲基汞和抗甲基汞物种的一个简单选择性策略
通讯作者姚祝军
英文摘要Methylmercury (MeHg+) is one of the most toxic mercury species targeting human nervous systems, and deficiency of a convenient and precise appraisal model for anti-MeHg+ treatment greatly slows down the step of developing clinically useful anti-MeHg+ agents. A simple visualization model has been demonstrated in this work for selective sensing of both MeHg+ and anti-MeHg+ agents in two continuous stages of one experiment in living cells, using a newly developed fluorescent pyrrolcoumarin probe. The developed sensing protocol shows great potential in the future applications of screening and evaluation of anti-MeHg+ agents. (C) 2012 Elsevier Ltd. All rights reserved.
学科主题生命有机化学
收录类别SCI
原文出处http://dx.doi.org/10.1016/j.tetlet.2012.04.113
语种英语
WOS记录号WOS:000306152500014
公开日期2013-08-23
源URL[http://202.127.28.38/handle/331003/28493]  
专题上海有机化学研究所_生命有机化学国家重点实验室
推荐引用方式
GB/T 7714
Mei DS,He BK,Chen L,et al. A simple selective protocol for continuous two-stage fluorescent sensing of both MeHg+ and anti-MeHg+ agents in living cells[J]. Tetrahedron Lett.,2012,53(27):3463-3466.
APA 梅德盛,何宝坤,陈磊,&姚祝军.(2012).A simple selective protocol for continuous two-stage fluorescent sensing of both MeHg+ and anti-MeHg+ agents in living cells.Tetrahedron Lett.,53(27),3463-3466.
MLA 梅德盛,et al."A simple selective protocol for continuous two-stage fluorescent sensing of both MeHg+ and anti-MeHg+ agents in living cells".Tetrahedron Lett. 53.27(2012):3463-3466.

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来源:上海有机化学研究所

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