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Biosynthetic Pathway for High Structural Diversity of a Common Dilactone Core in Antimycin Production
文献类型：期刊论文
| 作者 | Yan Y(闫岩) ; ZHANG LIHAN ; ITO TAKUYA ; Ju XD(瞿旭东) ; ASAKAWA YOSHINORI ; AWAKAWA TAKAYOSHI ; ABE IKURO ; Liu W(刘文) |
| 刊名 | Org. Lett.
 |
| 出版日期 | 2012 |
| 卷号 | 14期号:16页码:4142-4145 |
| ISSN号 | 1523-7060 |
| 其他题名 | Biosynthetic Pathway for High Structural Diversity of a Common Dilactone Core in Antimycin Production |
| 通讯作者 | 瞿旭东 ; 刘文 |
| 英文摘要 | We herein report comparative analysis of two versions of the biosynthetic gene clusters of antimycins, a natural product family possessing up to 44 distinct entities. The biosynthetic pathway of antimycins is amenable to the high structural variation of the substrates, supported by successes in heterologous expression of the ant cluster and in fluorine incorporation. The latter facilitated the investigation of the structure-activity relationship into the usually invariable 3-formamidosalicylic acid moiety of the molecules. |
| 学科主题 | 生命有机化学 |
| 收录类别 | SCI |
| 原文出处 | http://dx.doi.org/10.1021/ol301785x |
| 语种 | 英语 |
| WOS记录号 | WOS:000307526900028 |
| 公开日期 | 2013-08-23 |
| 源URL | [http://202.127.28.38/handle/331003/28559]  |
| 专题 | 上海有机化学研究所_生命有机化学国家重点实验室 |
| 推荐引用方式 GB/T 7714 | Yan Y,ZHANG LIHAN,ITO TAKUYA,et al. Biosynthetic Pathway for High Structural Diversity of a Common Dilactone Core in Antimycin Production[J]. Org. Lett.,2012,14(16):4142-4145. |
| APA | 闫岩.,ZHANG LIHAN.,ITO TAKUYA.,瞿旭东.,ASAKAWA YOSHINORI.,...&刘文.(2012).Biosynthetic Pathway for High Structural Diversity of a Common Dilactone Core in Antimycin Production.Org. Lett.,14(16),4142-4145. |
| MLA | 闫岩,et al."Biosynthetic Pathway for High Structural Diversity of a Common Dilactone Core in Antimycin Production".Org. Lett. 14.16(2012):4142-4145. |
入库方式： OAI收割
来源：上海有机化学研究所
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