Access to Both Enantiomers of alpha-Chloro-beta-keto Esters with a Single Chiral Ligand: Highly Efficient Enantioselective Chlorination of Cyclic beta-Keto Esters Catalyzed by Chiral Copper(II) and Zinc(II) Complexes of a Spiro-2,2 '-bischroman-Based Bisoxazoline Ligand
文献类型：期刊论文
| 作者 | Li J(李杰) ; Pan W(潘伟) ; Wang Z(王正) ; Zhang XM(张绪穆) ; Ding KL(丁奎岭) |
| 刊名 | Adv. Synth. Catal.
 |
| 出版日期 | 2012 |
| 卷号 | 354期号:10页码:1980-1986 |
| ISSN号 | 1615-4150 |
| 其他题名 | 用单一手性配体获得β-酮酸酯的两种对映异构体: SPANbox-Zn(II)和-Cu(II)络合物催化的β-酮酸酯的高对映选择性不对称卤化 |
| 通讯作者 | 丁奎岭 |
| 英文摘要 | The spiro-2,2'-bichroman-based chiral bisoxazoline ligands (SPANbox) were found to be highly efficient in copper(II)- and zinc(II)-catalyzed asymmetric chlorinations of cyclic beta-keto esters with N-chlorosuccinimide (NCS) as the chlorination reagent, to give the corresponding a-chloro-beta-keto esters in excellent yields in 530 min with ee values up to 97%. The copper(II) triflate and zinc(II) triflate complexes of a single SPANbox ligand demonstrated complementary results to each other with respect to the enantioselection, affording both antipodes of the chlorinated product enantiomers with good to excellent optical purities. |
| 学科主题 | 金属有机化学 |
| 收录类别 | SCI |
| 原文出处 | http://dx.doi.org/10.1002/adsc.201200088 |
| 语种 | 英语 |
| WOS记录号 | WOS:000306219000020 |
| 公开日期 | 2013-08-22 |
| 源URL | [http://202.127.28.38/handle/331003/27941]  |
| 专题 | 上海有机化学研究所_金属有机化学国家重点实验室 |
| 推荐引用方式 GB/T 7714 | Li J,Pan W,Wang Z,et al. Access to Both Enantiomers of alpha-Chloro-beta-keto Esters with a Single Chiral Ligand: Highly Efficient Enantioselective Chlorination of Cyclic beta-Keto Esters Catalyzed by Chiral Copper(II) and Zinc(II) Complexes of a Spiro-2,2 '-bischroman-Based Bisoxazoline Ligand[J]. Adv. Synth. Catal.,2012,354(10):1980-1986. |
| APA | 李杰,潘伟,王正,张绪穆,&丁奎岭.(2012).Access to Both Enantiomers of alpha-Chloro-beta-keto Esters with a Single Chiral Ligand: Highly Efficient Enantioselective Chlorination of Cyclic beta-Keto Esters Catalyzed by Chiral Copper(II) and Zinc(II) Complexes of a Spiro-2,2 '-bischroman-Based Bisoxazoline Ligand.Adv. Synth. Catal.,354(10),1980-1986. |
| MLA | 李杰,et al."Access to Both Enantiomers of alpha-Chloro-beta-keto Esters with a Single Chiral Ligand: Highly Efficient Enantioselective Chlorination of Cyclic beta-Keto Esters Catalyzed by Chiral Copper(II) and Zinc(II) Complexes of a Spiro-2,2 '-bischroman-Based Bisoxazoline Ligand".Adv. Synth. Catal. 354.10(2012):1980-1986. |
入库方式： OAI收割
来源：上海有机化学研究所
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