Enantioselective synthesis of 2,5-dihydrobenzo[b]azepine derivatives via iridium-catalyzed asymmetric allylic amination with 2-allylanilines and ring-closing-metathesis reaction
文献类型：期刊论文
| 作者 | Ye KY(叶克印) ; Dai LX(戴立信) ; You SL(游书力) |
| 刊名 | Org. Biomol. Chem.
 |
| 出版日期 | 2012 |
| 卷号 | 10期号:30页码:5932-5939 |
| ISSN号 | 1477-0520 |
| 其他题名 | 通过铱催化的2-烯丙基苯胺的不对称烯丙基胺化和关环复分解(RCM)实现的2,5-dihydrobenzo[b]azepine衍生物的手性合成 |
| 通讯作者 | 游书力 |
| 英文摘要 | Iridium-catalyzed asymmetric allylic amination of allylic carbonates with 2-allylanilines was realized. With a catalyst generated from 2 mol% of [Ir(dbcot)Cl](2) (dbcot = dibenzo[a,e]cyclooctatetraene) and 4 mol% of phosphoramidite ligand (L3), the amination products were obtained in up to 99% yield and 99% ee. Subjecting amination products to trifluoroacetyl protection and ring-closing-metathesis reaction provided an efficient synthesis of enantioenriched 2,5-dihydrobenzo[b]azepine derivatives. |
| 学科主题 | 金属有机化学 |
| 收录类别 | SCI |
| 原文出处 | http://dx.doi.org/10.1039/c2ob00036a |
| 语种 | 英语 |
| WOS记录号 | WOS:000306276800040 |
| 公开日期 | 2013-08-22 |
| 源URL | [http://202.127.28.38/handle/331003/28045]  |
| 专题 | 上海有机化学研究所_金属有机化学国家重点实验室 |
| 推荐引用方式 GB/T 7714 | Ye KY,Dai LX,You SL. Enantioselective synthesis of 2,5-dihydrobenzo[b]azepine derivatives via iridium-catalyzed asymmetric allylic amination with 2-allylanilines and ring-closing-metathesis reaction[J]. Org. Biomol. Chem.,2012,10(30):5932-5939. |
| APA | 叶克印,戴立信,&游书力.(2012).Enantioselective synthesis of 2,5-dihydrobenzo[b]azepine derivatives via iridium-catalyzed asymmetric allylic amination with 2-allylanilines and ring-closing-metathesis reaction.Org. Biomol. Chem.,10(30),5932-5939. |
| MLA | 叶克印,et al."Enantioselective synthesis of 2,5-dihydrobenzo[b]azepine derivatives via iridium-catalyzed asymmetric allylic amination with 2-allylanilines and ring-closing-metathesis reaction".Org. Biomol. Chem. 10.30(2012):5932-5939. |
入库方式： OAI收割
来源：上海有机化学研究所
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