One-Pot Synthesis of Pyrrolo[1,2-a]indoles by Chiral N-Triflyl Phosphoramide Catalyzed Friedel-Crafts Alkylation of 4,7-Dihydroindole with beta,gamma-Unsaturated alpha-Keto Esters
文献类型：期刊论文
| 作者 | Ceng M(曾蜜) ; Zhang W(张玮) ; You SL(游书力) |
| 刊名 | Chin. J. Chem.
 |
| 出版日期 | 2012 |
| 卷号 | 30期号:11页码:2615-2623 |
| ISSN号 | 1001-604X |
| 其他题名 | 通过手性磷酰胺催化的4,7-二氢吲哚与β,γ-不饱和 α-酮酸酯的Friedel-Crafts烷基化实现的吡咯[1,2-a]吲哚的一锅法合成 |
| 通讯作者 | 张玮 ; 游书力 |
| 英文摘要 | Chiral N-triflyl phosphoramide was found an efficient catalyst for the enantioselective Friedel-Crafts alkylation reaction of 4,7-dihydroindole with beta,gamma-unsaturated alpha-keto esters. In the presence of 5 mol% of the optimized catalyst, various pyrrolo[1,2-a]indoles were obtained in excellent enantioselectivity, moderate yields and up to 3:1 diastereoselectivity based on the one-pot synthesis including the Friedel-Crafts alkylation reaction and the subsequent p-benzoquinone oxidation. |
| 学科主题 | 金属有机化学 |
| 收录类别 | SCI |
| 原文出处 | http://dx.doi.org/10.1002/cjoc.201200759 |
| 语种 | 英语 |
| WOS记录号 | WOS:000311169300005 |
| 公开日期 | 2013-08-22 |
| 源URL | [http://202.127.28.38/handle/331003/28181]  |
| 专题 | 上海有机化学研究所_金属有机化学国家重点实验室 |
| 推荐引用方式 GB/T 7714 | Ceng M,Zhang W,You SL. One-Pot Synthesis of Pyrrolo[1,2-a]indoles by Chiral N-Triflyl Phosphoramide Catalyzed Friedel-Crafts Alkylation of 4,7-Dihydroindole with beta,gamma-Unsaturated alpha-Keto Esters[J]. Chin. J. Chem.,2012,30(11):2615-2623. |
| APA | 曾蜜,张玮,&游书力.(2012).One-Pot Synthesis of Pyrrolo[1,2-a]indoles by Chiral N-Triflyl Phosphoramide Catalyzed Friedel-Crafts Alkylation of 4,7-Dihydroindole with beta,gamma-Unsaturated alpha-Keto Esters.Chin. J. Chem.,30(11),2615-2623. |
| MLA | 曾蜜,et al."One-Pot Synthesis of Pyrrolo[1,2-a]indoles by Chiral N-Triflyl Phosphoramide Catalyzed Friedel-Crafts Alkylation of 4,7-Dihydroindole with beta,gamma-Unsaturated alpha-Keto Esters".Chin. J. Chem. 30.11(2012):2615-2623. |
入库方式： OAI收割
来源：上海有机化学研究所
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