Cell designs for optical biosensors
文献类型：专利
| 作者 | LOCKHART, MICHAEL D. |
| 发表日期 | 2002-09-12 |
| 专利号 | US20020126936A1 |
| 著作权人 | VERIDIAN SYSTEMS |
| 国家 | 美国 |
| 文献子类 | 发明申请 |
| 其他题名 | Cell designs for optical biosensors |
| 英文摘要 | An improved biosensor cell comprises a fluid-carrying chamber and a fixture configured to receive the chamber. The chamber includes one or more optical waveguides immersed in the fluid, each waveguide having an input end and an output end, both of which are optically accessible from outside the chamber. The fixture includes a first coupling or optical path for routing the source of light to one end of one of the optical waveguides, and a second coupling or optical path for routing the other end of the optical waveguide to the optical detector. The relationship between the fluid-carrying chamber and the fixture is such that the fluid-carrying chamber may be removed and replaced with the alignment of the ends of the waveguide and the optical coupling being physically maintained. The preferred embodiment uses a plurality of optical couplers, with partitions to establish a serpentine path around the couplers for comprehensive exposure to the fluid. Each coupler features a necked-down, fused region generating an evanescent field that extends into the fluid. The fluid-carrying chamber preferably includes an inlet and outlet to establish a flow around the optical waveguide. A chemical or biological constituent is disposed on the necked-down region within the evanescent field, such that binding alters the light exiting from the coupler for detection purposes. The fixture is also preferably configured to simultaneously receive a plurality of the fluid-carrying chambers, whether in a planar 1-by-X array or stacked to achieve an X-Y configuration. |
| 公开日期 | 2002-09-12 |
| 申请日期 | 2001-12-06 |
| 状态 | 失效 |
| 源URL | [http://ir.opt.ac.cn/handle/181661/52591]  |
| 专题 | 半导体激光器专利数据库 |
| 作者单位 | VERIDIAN SYSTEMS |
| 推荐引用方式 GB/T 7714 | LOCKHART, MICHAEL D.. Cell designs for optical biosensors. US20020126936A1. 2002-09-12. |
入库方式： OAI收割
来源：西安光学精密机械研究所
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