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The roles of TNFAIP2 in cancers and infectious diseases

文献类型：期刊论文

作者Lin Jia1; Yundong Shi1; Yi Wen2; Wei Li3,4; Jing Feng5; Ceshi Chen2
刊名Journal of Cellular and Molecular Medicine
出版日期2018
期号~页码:1–8
关键词Angiogenesis Inflammation Migration Nanotube Formation Proliferation Tnfaip2
DOI10.1111/jcmm.13822
英文摘要

TNFα‐induced protein 2 (TNFAIP2) is a primary response gene of TNFα. TNFAIP2 is
highly expressed in immune cells and the urinary bladder. The expression of
TNFAIP2 is regulated by multiple transcription factors and signalling pathways,
including NF‐κB, KLF5 and retinoic acid. Physiologically, TNFAIP2 appears to be a
multiple functional mediator not only for inflammation, angiogenesis and tunneling
nanotube (TNT) formation but also as a regulator of cell proliferation and migration.
The expression of TNFAIP2 is frequently abnormal in human cancers and in infec-
tious diseases. Due to its significant functions in cell proliferation, angiogenesis,
migration and invasion, TNFAIP2 could be a potential diagnostic biomarker and
therapeutic target for cancer.

语种英语
源URL[http://159.226.149.26:8080/handle/152453/12259]  
专题昆明动物研究所_动物模型与人类重大疾病机理重点实验室
通讯作者Ceshi Chen
作者单位1.Department of Biology, Yuxi Normal University, Yuxi, China
2.Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China
3.Department of Urology of the First People's Hospital of Yunnan Province, Kunming, China
4.Medical College of Kunming University of Science and Technology, Kunming, China
5.Department of Laboratory Medicine & Central Laboratory, Southern Medical University Affiliated Fengxian Hospital, Shanghai, China
推荐引用方式
GB/T 7714		 Lin Jia,Yundong Shi,Yi Wen,et al. The roles of TNFAIP2 in cancers and infectious diseases[J]. Journal of Cellular and Molecular Medicine,2018(~):1–8.
APA Lin Jia,Yundong Shi,Yi Wen,Wei Li,Jing Feng,&Ceshi Chen.(2018).The roles of TNFAIP2 in cancers and infectious diseases.Journal of Cellular and Molecular Medicine(~),1–8.
MLA Lin Jia,et al."The roles of TNFAIP2 in cancers and infectious diseases".Journal of Cellular and Molecular Medicine .~(2018):1–8.

入库方式： OAI收割

来源：昆明动物研究所

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