Recognizing Depression from the Microbiota-Gut-Brain Axis
文献类型：期刊论文
| 作者 | Liang, Shan2 ; Wu, Xiaoli1,2; Hu, Xu2; Wang, Tao2; Jin, Feng2
|
| 刊名 | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
 |
| 出版日期 | 2018-06-01 |
| 卷号 | 19期号:6页码:16 |
| ISSN号 | 1422-0067 |
| 关键词 | major depressive disorder brain-gut axis microbiota-gut-brain axis gut microbiota psychobiotics |
| DOI | 10.3390/ijms19061592 |
| 通讯作者 | Jin, Feng(jinfeng@psych.ac.cn) |
| 英文摘要 | Major depression is one of the leading causes of disability, morbidity, and mortality worldwide. The brain-gut axis functions are disturbed, revealed by a dysfunction of the brain, immune system, endocrine system, and gut. Traditional depression treatments all target the brain, with different drugs and/or psychotherapy. Unfortunately, most of the patients have never received any treatment. Studies indicate that gut microbiota could be a direct cause for the disorder. Abnormal microbiota and the microbiota-gut-brain dysfunction may cause mental disorders, while correcting these disturbance could alleviate depression. Nowadays, the gut microbiota modulation has become a hot topic in treatment research of mental disorders. Depression is closely related with the health condition of the brain-gut axis, and maintaining/restoring the normal condition of gut microbiota helps in the prevention/therapy of mental disorders. |
| WOS关键词 | ADULT HIPPOCAMPAL NEUROGENESIS ; IRRITABLE-BOWEL-SYNDROME ; PITUITARY-ADRENAL AXIS ; CENTRAL-NERVOUS-SYSTEM ; FECAL MICROBIOTA ; MATERNAL SEPARATION ; MAJOR DEPRESSION ; INTESTINAL MICROBIOTA ; PSYCHIATRIC-DISORDERS ; PROBIOTIC TREATMENT |
| WOS研究方向 | Biochemistry & Molecular Biology ; Chemistry |
| 语种 | 英语 |
| 出版者 | MDPI |
| WOS记录号 | WOS:000436506600047 |
| 源URL | [http://ir.psych.ac.cn/handle/311026/30388]  |
| 专题 | 心理研究所_中国科学院心理健康重点实验室 |
| 通讯作者 | Jin, Feng |
| 作者单位 | 1.Univ Chinese Acad Sci, Dept Psychol, Beijing 100049, Peoples R China 2.Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Beijing 100101, Peoples R China |
| 推荐引用方式 GB/T 7714 | Liang, Shan,Wu, Xiaoli,Hu, Xu,et al. Recognizing Depression from the Microbiota-Gut-Brain Axis[J]. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,2018,19(6):16. |
| APA | Liang, Shan,Wu, Xiaoli,Hu, Xu,Wang, Tao,&Jin, Feng.(2018).Recognizing Depression from the Microbiota-Gut-Brain Axis.INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,19(6),16. |
| MLA | Liang, Shan,et al."Recognizing Depression from the Microbiota-Gut-Brain Axis".INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 19.6(2018):16. |
入库方式： OAI收割
来源：心理研究所
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