Irpexlacte A-D, four new bioactive metabolites of endophytic fungus Irpex lacteus DR10-1 from the waterlogging tolerant plant Distylium chinense
文献类型：期刊论文
| 作者 | Duan, Xiao-Xiang2; Qin, Dan2; Song, Hong-Chuan3; Gao, Tian-Cong2; Zuo, Shi-Hao2; Yan, Xiao2; Wang, Jun-Qi2; Ding, Xiao1; Di, Ying-Tong1 ; Dong, Jin-Yan2
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| 刊名 | PHYTOCHEMISTRY LETTERS
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| 出版日期 | 2019-08-01 |
| 卷号 | 32页码:151-156 |
| 关键词 | Endophytic fungus Distylium chinense Bioactive metabolites Irpex lacteus |
| ISSN号 | 1874-3900 |
| DOI | 10.1016/j.phytol.2019.06.001 |
| 通讯作者 | Dong, Jin-Yan(donjyaa@swu.edu.cn) |
| 英文摘要 | One new tremulane sesquiterpene, irpexlacte A (1), and three new furan derivatives, irpexlacte B-D (2-4), were isolated from the endophytic fungus Irpex lacteus DR10-1 waterlogging tolerant plant Distylium chinense, together with two known ones, irlactin E (5) and 3 beta-hydroxycinnamolide (6). Structures of these metabolites were characterized by HRESIMS and NMR spectroscopic methods. The antibacterial, anticancer and antioxidant activities of new compounds (1-4) were evaluated. 1-4 showed moderate antibacterial activity against Pseudomonas aeruginosa with MIC values ranging from 23.8 to 35.4 mu M. 1 and 4 showed remarkable antioxidant activity with IC50 values of 2.50 and 5.75 mu M respectively, which may contribute to the survival of D. chinense under waterlogging stress by eliminating the reactive oxygen species (ROS). Additionally, 1-5 may play important role on the sexual/asexual state of I. lacteus. |
| WOS研究方向 | Plant Sciences ; Pharmacology & Pharmacy |
| 语种 | 英语 |
| WOS记录号 | WOS:000476725000029 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/68181]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 通讯作者 | Dong, Jin-Yan |
| 作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China 2.Southwest Univ, Sch Life Sci, Chongqing Key Lab Plant Resource Conservat & Germ, Chongqing 400715, Peoples R China 3.Yunnan Normal Univ, Sch Energy & Environm Sci, Solar Energy Res Inst, Kunming 650092, Yunnan, Peoples R China |
| 推荐引用方式 GB/T 7714 | Duan, Xiao-Xiang,Qin, Dan,Song, Hong-Chuan,et al. Irpexlacte A-D, four new bioactive metabolites of endophytic fungus Irpex lacteus DR10-1 from the waterlogging tolerant plant Distylium chinense[J]. PHYTOCHEMISTRY LETTERS,2019,32:151-156. |
| APA | Duan, Xiao-Xiang.,Qin, Dan.,Song, Hong-Chuan.,Gao, Tian-Cong.,Zuo, Shi-Hao.,...&Dong, Jin-Yan.(2019).Irpexlacte A-D, four new bioactive metabolites of endophytic fungus Irpex lacteus DR10-1 from the waterlogging tolerant plant Distylium chinense.PHYTOCHEMISTRY LETTERS,32,151-156. |
| MLA | Duan, Xiao-Xiang,et al."Irpexlacte A-D, four new bioactive metabolites of endophytic fungus Irpex lacteus DR10-1 from the waterlogging tolerant plant Distylium chinense".PHYTOCHEMISTRY LETTERS 32(2019):151-156. |
入库方式： OAI收割
来源：昆明植物研究所
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