Chemical constituents from plant endophytic fungus Alternaria alternata
文献类型：期刊论文
| 作者 | Wang, Ju-Tao3,4; Ma, Zong-Hui3; Wang, Guo-Kai3,4; Xu, Feng-Qing3,4; Yu, Yang1,2; Wang, Gang3,4; Peng, Dai-Yin3,4; Liu, Jin-Song3,4 |
| 刊名 | NATURAL PRODUCT RESEARCH
 |
| 出版日期 | 2019-07-13 |
| 页码 | 8 |
| 关键词 | Alternaria alternata Paeonia lactiflora benzo-alpha-pyrone derivatives cytotoxic activity |
| ISSN号 | 1478-6419 |
| DOI | 10.1080/14786419.2019.1639699 |
| 通讯作者 | Peng, Dai-Yin(pengdy@ahtcm.edu.cn) ; Liu, Jin-Song(jinsongliu@ahtcm.edu.cn) |
| 英文摘要 | Five new natural compounds (1-5) along with four known ones, involving dibenzo-alpha-pyrone derivatives, a benzo-gamma-pyrone derivative and an amide-type compound were obtained from Alternaria alternata, an endophyte isolated from Paeonia lactiflora. The structures of these isolates were elucidated by intensive analysis of spectroscopic data including NMR, HRMS (ESI and EI), UV and IR spectra. Compounds (1-4) were evaluated for their cytotoxicities against five selected human tumourtumour cell lines (A-549, MDA-MB-231, MCF-7, KB and KB-VIN), and compound 3 exhibited activities against MDA-MB-231and MCF-7 with IC50 values of 20.1 mu M and 32.2 mu M. [GRAPHICS] . |
| WOS研究方向 | Chemistry ; Pharmacology & Pharmacy |
| 语种 | 英语 |
| WOS记录号 | WOS:000478316400001 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/68202]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 通讯作者 | Peng, Dai-Yin; Liu, Jin-Song |
| 作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming, Yunnan, Peoples R China 2.Univ Chinese Acad Sci, Beijing, Peoples R China 3.Anhui Univ Chinese Med, Sch Pharm, Anhui Key Lab Modern Chinese Mat Med, Hefei, Anhui, Peoples R China 4.Synerget Innovat Ctr Anhui Authent Chinese Med Qu, Hefei, Anhui, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang, Ju-Tao,Ma, Zong-Hui,Wang, Guo-Kai,et al. Chemical constituents from plant endophytic fungus Alternaria alternata[J]. NATURAL PRODUCT RESEARCH,2019:8. |
| APA | Wang, Ju-Tao.,Ma, Zong-Hui.,Wang, Guo-Kai.,Xu, Feng-Qing.,Yu, Yang.,...&Liu, Jin-Song.(2019).Chemical constituents from plant endophytic fungus Alternaria alternata.NATURAL PRODUCT RESEARCH,8. |
| MLA | Wang, Ju-Tao,et al."Chemical constituents from plant endophytic fungus Alternaria alternata".NATURAL PRODUCT RESEARCH (2019):8. |
入库方式： OAI收割
来源：昆明植物研究所
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