Neo-clerodane diterpenoids from aerial parts of Salvia hispanica L. and their cardioprotective effects
文献类型：期刊论文
| 作者 | Fan, Min1,2 ; Luo, Dan1; Peng, Li-Yan1; Li, Xiao-Nian1; Wu, Xing-De1; Ji, Xu1; Zhao, Qin-Shi1
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| 刊名 | PHYTOCHEMISTRY
 |
| 出版日期 | 2019-10-01 |
| 卷号 | 166页码:11 |
| 关键词 | Salvia hispanica L. (Lamiaceae) Chia Neo-clerodane diterpenoids Hispanins A-J Single crystal X-ray diffraction analysis Cardioprotective effects |
| ISSN号 | 0031-9422 |
| DOI | 10.1016/j.phytochem.2019.112065 |
| 通讯作者 | Wu, Xing-De(wuxingde@mail.kib.ac.cn) ; Ji, Xu(jixu@mail.kib.ac.cn) ; Zhao, Qin-Shi(qinshizhao@mail.kib.ac.cn) |
| 英文摘要 | Ten undescribed neo-clerodane diterpenoids, named hispanins A-J, together with six known ones, were isolated from the aerial parts of Salvia hispanica L. Their structures were established by extensive spectroscopic analysis. The absolute configurations of the undescribed compounds were determined by the ECD data and single crystal X-ray diffraction analysis. Hispanins B and C represented the first neo-clerodane diterpenoids with a unique oxygen bridge between C-19 and C-20. All isolated compounds were evaluated for their protective effects against H2O2-induced cardiomyocyte injury. Five of these compounds showed significant cardioprotective effects. |
| WOS研究方向 | Biochemistry & Molecular Biology ; Plant Sciences |
| 语种 | 英语 |
| WOS记录号 | WOS:000484650500014 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/68629]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 通讯作者 | Wu, Xing-De; Ji, Xu; Zhao, Qin-Shi |
| 作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650204, Yunnan, Peoples R China 2.Dali Univ, Coll Pharmaceut Sci, Dali 671000, Peoples R China |
| 推荐引用方式 GB/T 7714 | Fan, Min,Luo, Dan,Peng, Li-Yan,et al. Neo-clerodane diterpenoids from aerial parts of Salvia hispanica L. and their cardioprotective effects[J]. PHYTOCHEMISTRY,2019,166:11. |
| APA | Fan, Min.,Luo, Dan.,Peng, Li-Yan.,Li, Xiao-Nian.,Wu, Xing-De.,...&Zhao, Qin-Shi.(2019).Neo-clerodane diterpenoids from aerial parts of Salvia hispanica L. and their cardioprotective effects.PHYTOCHEMISTRY,166,11. |
| MLA | Fan, Min,et al."Neo-clerodane diterpenoids from aerial parts of Salvia hispanica L. and their cardioprotective effects".PHYTOCHEMISTRY 166(2019):11. |
入库方式： OAI收割
来源：昆明植物研究所
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