Hybrid isoquinolines from Thalictrum foetidum: a new type of aporphine inhibiting Staphylococcus aureus by combined mechanisms
文献类型：期刊论文
| 作者 | Ding, Cai-Feng2,3 ; Zhang, Rong-Ping5,6; Yu, Hao-Fei1,5,6; Yang, Jing3; Qin, Xu-Jie3; Dai, Zhi3; Liu, Ya-Ping3; Lu, Qiu-Min4; Lai, Ren4; Luo, Xiao-Dong1,3
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| 刊名 | ORGANIC CHEMISTRY FRONTIERS
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| 出版日期 | 2019-10-07 |
| 卷号 | 6期号:19页码:3428-3434 |
| ISSN号 | 2052-4129 |
| DOI | 10.1039/c9qo00737g |
| 通讯作者 | Lai, Ren(rlai@mail.kib.ac.cn) ; Luo, Xiao-Dong(xdluo@mail.kib.ac.cn) |
| 英文摘要 | Thalfoetines A-D (1-4), unique hybrid aporphine alkaloids with a C-7 aromatic unit formed by a new C-C bond linking two building blocks, were isolated from Thalictrum foetidum. Their structures were elucidated by extensive spectroscopic and computational analysis. They inhibited bacteria significantly, and compound 1 damaged the cell structure of Staphylococcus aureus and inhibited its DNA synthesis. |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000487508600017 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/69470]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 通讯作者 | Lai, Ren; Luo, Xiao-Dong |
| 作者单位 | 1.Yunnan Univ, Sch Chem Sci & Technol, Key Lab Med Chem Nat Resource, Minist Educ & Yunnan Prov, Kunming 650091, Yunnan, Peoples R China 2.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China 3.Chinese Acad Sci, Kunming Inst Bot, Key Lab Phytochem & Plant Resources West China, Kunming 650201, Yunnan, Peoples R China 4.Chinese Acad Sci & Yunnan Prov, Key Lab Anim Models & Human Dis Mech, Kunming Inst Zool, Kunming 650223, Yunnan, Peoples R China 5.Kunming Med Univ, Sch Pharmaceut Sci, Kunming 650500, Yunnan, Peoples R China 6.Kunming Med Univ, Yunnan Key Lab Pharmacologyf Nat Prod, Kunming 650500, Yunnan, Peoples R China |
| 推荐引用方式 GB/T 7714 | Ding, Cai-Feng,Zhang, Rong-Ping,Yu, Hao-Fei,et al. Hybrid isoquinolines from Thalictrum foetidum: a new type of aporphine inhibiting Staphylococcus aureus by combined mechanisms[J]. ORGANIC CHEMISTRY FRONTIERS,2019,6(19):3428-3434. |
| APA | Ding, Cai-Feng.,Zhang, Rong-Ping.,Yu, Hao-Fei.,Yang, Jing.,Qin, Xu-Jie.,...&Luo, Xiao-Dong.(2019).Hybrid isoquinolines from Thalictrum foetidum: a new type of aporphine inhibiting Staphylococcus aureus by combined mechanisms.ORGANIC CHEMISTRY FRONTIERS,6(19),3428-3434. |
| MLA | Ding, Cai-Feng,et al."Hybrid isoquinolines from Thalictrum foetidum: a new type of aporphine inhibiting Staphylococcus aureus by combined mechanisms".ORGANIC CHEMISTRY FRONTIERS 6.19(2019):3428-3434. |
入库方式： OAI收割
来源：昆明植物研究所
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