Sex differences in resting-state cerebral activity alterations in internet gaming disorder
文献类型：期刊论文
| 作者 | Sun, Yawen2; Wang, Yao2; Han, Xu2; Jiang, Wenqing1; Ding, Weina2; Cao, Mengqiu2; Du, Yasong1; Lin, Fuchun3; Xu, Jianrong2; Zhou, Yan2 |
| 刊名 | BRAIN IMAGING AND BEHAVIOR
 |
| 出版日期 | 2019-10-01 |
| 卷号 | 13期号:5页码:1406-1417 |
| ISSN号 | 1931-7557 |
| 关键词 | Resting-state functional magnetic resonance imaging Internet gaming disorder Sex differences Amplitude of low-frequency fluctuation Functional connectivity |
| DOI | 10.1007/s11682-018-9955-4 |
| 英文摘要 | Although evidence has shown that the prevalence rates of Internet gaming disorder (IGD) differ between males and females, few studies have examined whether such sex differences extend to brain function. This study aimed to explore the sex differences in resting-state cerebral activity alterations in IGD. Thirty male participants with IGD (IGDm), 23 female participants with IGD (IGDf), and 30 male and 22 female age-matched healthy controls (HC) underwent resting-state functional MRI. Maps of the amplitude of low-frequency fluctuation (ALFF) and functional connectivity (FC) were constructed. A two-factor ANCOVA model was performed, with sex and diagnosis as the between-subject factors. Then, post hoc pair-wise comparisons were performed using two-sample t-tests within the interaction masks. The Barratt Impulsiveness Scale-11 (BIS-11) was used to assess the behavioral inhibition function. We found that the ALFF values in the orbital part of the left superior frontal gyrus (SFG) were lower in IGDm than in HCm, which were negatively correlated with BIS-11 scores. IGDm also demonstrated lower connectivity between the orbital part of the left SFG and the posterior cingulate cortex (PCC), the right angular gyrus, and the right dorsolateral prefrontal cortex than HCm. Furthermore, IGDm had lower seed connectivity between the orbital part of the left SFG and the PCC than ICDf. Our findings suggest that (1) the altered ALFF values in the orbital part of the left SFG represent a clinically relevant biomarker for the behavioral inhibition function of IGDm; (2) IGD may interact with sex-specific patterns of FC in male and female subjects. |
| WOS关键词 | DEFAULT MODE NETWORK ; FUNCTIONAL CONNECTIVITY ; INHIBITORY CONTROL ; PREFRONTAL CORTEX ; FRONTOSTRIATAL CIRCUITS ; ADDICTION DISORDER ; HEALTHY-MALES ; IMPULSIVITY ; RISK ; PREVALENCE |
| 资助项目 | National Natural Science Foundation of China[81571650] ; National Natural Science Foundation of China[81571757] ; Shanghai Municipal Education Commission-Gaofeng Clinical Medicine Grant Support[20172013] ; Shanghai Science and Technology Committee Medical Guide Project[17411964300] ; Medical Engineering Cross Research Foundation of Shanghai Jiao Tong University[YG2017QN47] ; Research Seed Fund of Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University[RJZZ17-016] ; Incubating Program for Clinical Research and Innovation of Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University[PYIII-17-027] ; Incubating Program for Clinical Research and Innovation of Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University[PYIV-17-003] ; Frontier Scientific Significant Breakthrough Project of CAS[QYZDB-SSW-SLH046] |
| WOS研究方向 | Neurosciences & Neurology |
| 语种 | 英语 |
| 出版者 | SPRINGER |
| WOS记录号 | WOS:000484959700021 |
| 资助机构 | National Natural Science Foundation of China ; National Natural Science Foundation of China ; Shanghai Municipal Education Commission-Gaofeng Clinical Medicine Grant Support ; Shanghai Municipal Education Commission-Gaofeng Clinical Medicine Grant Support ; Shanghai Science and Technology Committee Medical Guide Project ; Shanghai Science and Technology Committee Medical Guide Project ; Medical Engineering Cross Research Foundation of Shanghai Jiao Tong University ; Medical Engineering Cross Research Foundation of Shanghai Jiao Tong University ; Research Seed Fund of Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University ; Research Seed Fund of Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University ; Incubating Program for Clinical Research and Innovation of Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University ; Incubating Program for Clinical Research and Innovation of Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University ; Frontier Scientific Significant Breakthrough Project of CAS ; Frontier Scientific Significant Breakthrough Project of CAS ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; Shanghai Municipal Education Commission-Gaofeng Clinical Medicine Grant Support ; Shanghai Municipal Education Commission-Gaofeng Clinical Medicine Grant Support ; Shanghai Science and Technology Committee Medical Guide Project ; Shanghai Science and Technology Committee Medical Guide Project ; Medical Engineering Cross Research Foundation of Shanghai Jiao Tong University ; Medical Engineering Cross Research Foundation of Shanghai Jiao Tong University ; Research Seed Fund of Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University ; Research Seed Fund of Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University ; Incubating Program for Clinical Research and Innovation of Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University ; Incubating Program for Clinical Research and Innovation of Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University ; Frontier Scientific Significant Breakthrough Project of CAS ; Frontier Scientific Significant Breakthrough Project of CAS ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; Shanghai Municipal Education Commission-Gaofeng Clinical Medicine Grant Support ; Shanghai Municipal Education Commission-Gaofeng Clinical Medicine Grant Support ; Shanghai Science and Technology Committee Medical Guide Project ; Shanghai Science and Technology Committee Medical Guide Project ; Medical Engineering Cross Research Foundation of Shanghai Jiao Tong University ; Medical Engineering Cross Research Foundation of Shanghai Jiao Tong University ; Research Seed Fund of Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University ; Research Seed Fund of Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University ; Incubating Program for Clinical Research and Innovation of Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University ; Incubating Program for Clinical Research and Innovation of Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University ; Frontier Scientific Significant Breakthrough Project of CAS ; Frontier Scientific Significant Breakthrough Project of CAS ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; Shanghai Municipal Education Commission-Gaofeng Clinical Medicine Grant Support ; Shanghai Municipal Education Commission-Gaofeng Clinical Medicine Grant Support ; Shanghai Science and Technology Committee Medical Guide Project ; Shanghai Science and Technology Committee Medical Guide Project ; Medical Engineering Cross Research Foundation of Shanghai Jiao Tong University ; Medical Engineering Cross Research Foundation of Shanghai Jiao Tong University ; Research Seed Fund of Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University ; Research Seed Fund of Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University ; Incubating Program for Clinical Research and Innovation of Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University ; Incubating Program for Clinical Research and Innovation of Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University ; Frontier Scientific Significant Breakthrough Project of CAS ; Frontier Scientific Significant Breakthrough Project of CAS |
| 源URL | [http://ir.wipm.ac.cn/handle/112942/14865]  |
| 专题 | 中国科学院武汉物理与数学研究所 |
| 通讯作者 | Zhou, Yan |
| 作者单位 | 1.Shanghai Jiao Tong Univ, Shanghai Mental Hlth Ctr, Dept Child & Adolescent Psychiat, Shanghai 200030, Peoples R China 2.Shanghai Jiao Tong Univ, Sch Med, Ren Ji Hosp, Dept Radiol, Shanghai 200127, Peoples R China 3.Chinese Acad Sci, Natl Ctr Magnet Resonance Wuhan, State Key Lab Magnet Resonance & Atom & Mol Phys, Wuhan Inst Phys & Math, Wuhan 430071, Hubei, Peoples R China |
| 推荐引用方式 GB/T 7714 | Sun, Yawen,Wang, Yao,Han, Xu,et al. Sex differences in resting-state cerebral activity alterations in internet gaming disorder[J]. BRAIN IMAGING AND BEHAVIOR,2019,13(5):1406-1417. |
| APA | Sun, Yawen.,Wang, Yao.,Han, Xu.,Jiang, Wenqing.,Ding, Weina.,...&Zhou, Yan.(2019).Sex differences in resting-state cerebral activity alterations in internet gaming disorder.BRAIN IMAGING AND BEHAVIOR,13(5),1406-1417. |
| MLA | Sun, Yawen,et al."Sex differences in resting-state cerebral activity alterations in internet gaming disorder".BRAIN IMAGING AND BEHAVIOR 13.5(2019):1406-1417. |
入库方式： OAI收割
来源：武汉物理与数学研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。